Discover a range of exceptional per diem Medical Surgical Registered Nurse opportunities that stand out as the highest-paying positions currently available through AMN Healthcare in the vibrant city of San Diego, California. These roles not only offer competitive compensation but also provide the flexibility and support you need to thrive in your nursing career. Explore the listings below to find a perfect match that aligns with your skills and aspirations in a picturesque location known for its stunning coastlines and dynamic healthcare community. Your next rewarding chapter in nursing awaits!
At AMN Healthcare, we understand the unique needs of Nursing professionals seeking flexible per diem Medical Surgical opportunities in vibrant San Diego. With over 40 years of experience as a staffing leader, we proudly support more than 10,000 healthcare workers annually, offering tailored job placements that enhance both career satisfaction and work-life balance. Our dedicated team provides personalized guidance throughout your nursing career, ensuring you find the right fit that aligns with your professional goals and expertise. Join us at AMN Healthcare and take the next step in your nursing journey while enjoying the beautiful coastal city of San Diego.
Here are some of the highest paying Medical Surgical RN jobs currently available in San Diego, California:
AMN Healthcare currently has 3 Medical Surgical Registered Nurse jobs available in San Diego, with start dates as early as 12/18/25. As of December 4, 2025, the average hourly pay for a Medical Surgical RN in San Diego was $64, with the range in pay between $60 and $71.
If San Diego isn’t your only option, we also have Medical Surgical Registered Nurse jobs nearby in Fountain Valley (82.4 miles), Riverside (86.5 miles) and Los Alamitos (91.6 miles). Or, if you’re looking for cities with the largest variety of Medical Surgical Registered Nurse jobs available currently, you should try Osseo (8 jobs), Tucson (8 jobs), Denver (7 jobs), New York City (6 jobs), and Wichita (4 jobs).
If you’re interested, just Apply Now and we’ll match you with a recruiter for more personalized service!
If you’re a Medical Surgical RN curious about Per Diem job trends in San Diego, CA, AMN Healthcare has successfully filled 1 similar positions in the area, providing insight into the opportunities you could expect. These previously filled roles offered competitive pay, with an average hourly rate of $62 and a range from $60 to $64 per hour, showcasing the strong earning potential for professionals in this field.
Positions were located in key zip codes, including 92123 and 92120, at reputable facilities such as Kaiser Permanente Zion Medical Center. These placements reflect the high demand for skilled Medical Surgical RNs in San Diego’s thriving healthcare landscape. With AMN Healthcare, you can count on access to similar roles tailored to your expertise and career goals. Explore how you can join this network of professionals and take the next step in your career today!
Here’s a look at some of the most recently filled Medical Surgical RN positions in San Diego, giving you a glimpse into the competitive pay rates and opportunities available.
As a Registered Nurse (RN) specializing in Medical Surgical care in San Diego, California, you can expect to work in a diverse range of healthcare settings that cater to various patient needs. San Diego is home to a multitude of renowned hospitals, outpatient clinics, and rehabilitation centers, providing ample opportunities within high-acuity environments such as trauma centers and specialty units, as well as community hospitals focusing on general medical-surgical nursing. In these roles, Medical Surgical RNs are tasked with performing comprehensive patient assessments, managing post-operative care, administering medications, and collaborating with interdisciplinary teams to develop and implement effective care plans. Moreover, given San Diego’s vibrant healthcare landscape, you may also have access to specialized training programs and continued education opportunities that enhance your professional growth while contributing to a collaborative and patient-centered approach to care.
As a Medical Surgical RN considering a per diem position in sunny San Diego, California, you’ll be drawn not just by the promise of flexible scheduling, but also by the vibrant lifestyle the city offers. San Diego is celebrated for its mild, Mediterranean climate, with temperatures averaging in the mid-70s year-round, perfect for outdoor enthusiasts. Explore popular neighborhoods like the historic Gaslamp Quarter or family-friendly La Jolla, where stunning coastal views and an array of dining options await. In your downtime, you can soak up the sun at beautiful beaches, indulge in world-renowned cuisine, or visit attractions like the San Diego Zoo and Balboa Park. Embrace the opportunity to enjoy a fulfilling career while living in one of America’s most desirable cities!
Discover a variety of exciting per diem Medical Surgical Registered Nurse opportunities right here in beautiful San Diego. Browse through the listings below and find the perfect job that aligns with your career aspirations and lifestyle!
As you navigate the dynamic landscape of per diem Medical Surgical Registered Nurse opportunities in San Diego, the data presented below serves as a valuable resource to enhance your understanding of the current job market. By reviewing the insights into average pay trends from the past three months, as well as the historical pay range for the last year, you’ll gain a clearer picture of the compensation you can expect in this vital field.
Additionally, the breakdown of healthcare facilities in San Diego that are actively hiring will empower you to target your job search more effectively. Whether you’re a seasoned RN or new to the field, these statistics not only illuminate the opportunities available but also help you make informed decisions as you seek a role that aligns with your career goals and financial expectations. Dive into the data and take the next step in your professional journey!
Current requirements for a Medical Surgical Registered Nurse per diem position in San Diego typically include a valid California RN license, clinical experience in a medical-surgical environment, and proficiency in basic patient care techniques. Preferred qualifications often involve certifications such as BLS and ACLS, along with previous hospital experience to ensure familiarity with the fast-paced medical setting.
Medical Surgical Registered Nurse per diem jobs in San Diego, California are typically available at acute care hospitals, rehabilitation centers, and outpatient clinics. These facilities often seek flexible nursing staff to accommodate varying patient volumes and skilled nursing needs.
When looking for a per diem job in San Diego, a Medical Surgical RN should inquire about competitive pay rates, flexible scheduling, and opportunities for professional development. Additionally, it’s important to ask about benefits such as health insurance options, retirement plans, and support for continuing education.
A per diem Medical Surgical RN may seek a job in San Diego for its appealing climate and vibrant lifestyle, which can enhance work-life balance. Additionally, the city’s diverse healthcare facilities provide a range of opportunities for professional growth and networking.
Some popular neighborhoods in San Diego for a per diem Medical Surgical RN include Hillcrest, known for its vibrant atmosphere and proximity to healthcare facilities, as well as La Jolla, which offers beautiful coastal views and a relaxed lifestyle. Downtown San Diego is also appealing for its urban convenience and access to numerous hospitals. Another attractive area is Mission Valley, which provides a central location with various amenities and easy commutes to healthcare centers.
A per diem Medical Surgical RN should look for a supportive work environment that fosters open communication and collaboration among staff. Additionally, it’s important to consider flexible scheduling options that align with personal commitments while ensuring adequate patient care. Lastly, evaluating the resources available for continuing education and professional development can greatly enhance job satisfaction and career growth.
At AMN Healthcare, we understand the dynamic landscape of healthcare employment, particularly in sought-after locations like San Diego, California. For per diem Medical Surgical Registered Nurses seeking flexible opportunities, we’ve curated a list of recent job placements that exemplify the range of positions commonly available in this critical field. This resource not only highlights the diverse settings and specific requirements of MS roles but also serves as a valuable tool for aspiring candidates to gain insights into current market trends and employer expectations. Whether you’re looking to enhance your experience or explore new environments, these listings provide a snapshot of the vibrant opportunities awaiting talented nurses like you in San Diego.
One city that shares similar characteristics with San Diego for Medical Surgical RNs is Phoenix, Arizona. Like San Diego, Phoenix offers a warm climate with plenty of sunshine year-round, which is appealing to those who enjoy outdoor activities. The cost of living in Phoenix is generally lower than in San Diego, making housing more affordable while still offering a variety of options, from urban apartments to suburban homes. In terms of pay, medical professionals can expect competitive salaries, though slightly lower than San Diego, the trade-off can be beneficial given the overall lower living costs. The city’s vibrant culture, with plenty of outdoor recreation options and a growing healthcare industry, contributes to a lively lifestyle.
Another comparable city is Austin, Texas, which boasts a thriving tech scene and a growing healthcare sector. Medical Surgical RNs in Austin often find competitive salaries that are on par with San Diego’s, but the cost of living is significantly lower, making it an attractive option for those looking to balance their budget. Housing in Austin has the advantage of a range of choices from downtown condos to family-friendly neighborhoods. Known for its live music scene, outdoor festivals, and a strong sense of community, Austin offers a rich lifestyle that emphasizes both work and play in a similar fashion to San Diego.
Charlotte, North Carolina, stands out as a third city that resembles San Diego in terms of job opportunities for RNs. The cost of living in Charlotte is considerably lower than in San Diego, enabling residents to enjoy affordable housing options while still benefiting from a growing healthcare market, especially in its numerous hospitals and medical facilities. While salaries for RNs may be somewhat lower than the West Coast standard, the lower living expenses often allow for a comfortable quality of life. Charlotte combines southern charm with a modern urban setting, offering outdoor activities, sports events, and a variety of cultural amenities that promote a balanced lifestyle.
A fourth city to consider is Tampa, Florida, which mirrors San Diego’s appeal with a warm climate, beautiful beaches, and a wide array of recreational activities. The cost of living in Tampa is notably lower than San Diego, with diverse housing opportunities ranging from waterfront properties to suburban developments. While salaries for Medical Surgical RNs may be a bit lower, the overall affordability allows for a comparable quality of life. Tampa also boasts a vibrant nightlife, numerous parks, and is close to major attractions, making it a great city for those who appreciate an active lifestyle.
Lastly, Denver, Colorado, represents another city that can be likened to San Diego for RNs in the medical-surgical field. Although the cost of living is on the rise, housing options range widely from urban apartments to spacious homes in nearby suburbs, offering various choices depending on lifestyle preferences. Salaries for healthcare positions in Denver are competitive, typically aligning with a higher cost of living, but the city compensates with its stunning natural surroundings and abundant outdoor activities. Denver’s cultural scene and lifestyle full of sports, arts, and outdoor adventures provide an engaging environment similar to that of San Diego, appealing to both work professionals and those seeking a fulfilling personal lifestyle.
San Diego boasts a diverse array of healthcare facilities that consistently seek qualified Medical Surgical Registered Nurses for per diem opportunities, catering to the dynamic needs of the community. From bustling hospitals to specialty clinics, these institutions offer flexible staffing solutions, ensuring that nursing professionals can find rewarding positions that fit their schedules while providing essential patient care.