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Registered Nurse Travel Jobs in South Carolina

Advance Your Career with Travel RN Jobs in South Carolina

At AMN Healthcare, we understand that nursing professionals are seeking opportunities that not only advance their careers but also offer the flexibility and adventure that travel nursing provides. With over 40 years of experience as a staffing leader in the healthcare industry, we proudly support more than 10,000 workers annually, helping them find travel Registered Nurse jobs that fit their specialized skills and aspirations. In South Carolina, we have a diverse range of opportunities available across various critical care and specialty areas, including Medical Surgical, Telemetry, Emergency Room, Intensive Care Unit, Labor & Delivery, and many more. Our dedicated team offers personalized guidance and support throughout your career, ensuring you have the resources you need to succeed and thrive in your travel nursing journey. Whether you’re looking for new challenges in a bustling emergency room or a tranquil home health setting, AMN Healthcare is committed to helping you achieve your professional goals while exploring beautiful South Carolina.

Explore High Paying Travel Registered Nurse Jobs that AMN Healthcare offers in South Carolina

Explore these top-paying jobs currently available in South Carolina:

AMN Healthcare currently has 17 travel Registered Nurse job opportunities available across South Carolina, offering competitive weekly pay ranging from $1,495 to $2,228, with an average of $1,889 per week. These positions span specialties like Home Health Registered Nurse, Postpartum, and RN Case Manager, with opportunities in Rock Hill (5 jobs), Florence (3 jobs), Charleston (2 jobs), Fort Mill (2 jobs), and Hilton Head (2 jobs), some of South Carolina’s most in-demand locations.

Whether you’re looking for an immediate start or planning ahead, multiple assignments are available with start dates as early as 12/08/25 (3 jobs), 12/15/25 (4 jobs), 12/18/25 (5 jobs), and 12/29/25 (5 jobs). With openings in zip codes like 29732, 29406, 29926, 29506, 29464 and 29401, AMN Healthcare provides access to rewarding travel positions in both urban and suburban settings. If you’re ready to take the next step in your career with a high-paying, flexible travel job in South Carolina, click Apply Now and our expert team will help you find the right fit and guide you through every step of the process.

Recent RN Job Placements in South Carolina

AMN Healthcare has successfully placed 710 Travel Registered Nurse professionals in high-demand positions across South Carolina, offering competitive pay and career-enhancing experiences. These previously filled jobs had weekly pay ranging from $828 to $3,146, with an average of $1,852, reflecting the strong earning potential for Home Health Hospice Registered Nurse, Long Term Acute Care Registered Nurse, and Outpatient Registered Nurse professionals. Positions were filled in top healthcare facilities such as Bon Secours St. Francis Downtown (Simplify), East Cooper Medical Center, and McLeod Health Cheraw (FKA: Chesterfield General Hospital) with assignments located in zip codes like 29732, 29926, 29406, 29506, 29572, and 29520, demonstrating a steady demand for skilled Registered Nurse professionals.

By reviewing these past placements, you can get a clear picture of the types of opportunities available and the earning potential in Travel Registered Nurse positions throughout South Carolina. If you’re ready to explore new assignments with top facilities and competitive pay, AMN Healthcare is here to connect you with the right job and provide expert support throughout your travel career.

Review some of the recently filled Registered Nurse positions in South Carolina and gain insight into the pay rates and opportunities available.

  • Cardiovascular ICU Registered Nurse making $2,228 per week filled on 12/3/25
  • Intensive Care Unit RN making $1,955 per week filled on 12/3/25
  • Intensive Care Unit RN making $1,955 per week filled on 12/3/25

What Types of Facilities and Work Can Registered Nurse Professionals Expect in South Carolina?

At AMN Healthcare, we recognize that Registered Nurses in South Carolina play a vital role in the diverse landscape of healthcare facilities throughout the state. RNs can expect to find rewarding career opportunities in a variety of settings, including bustling hospitals, serene long-term care facilities, outpatient clinics, and specialized treatment centers. In addition to traditional roles in medical-surgical units and emergency departments, nurses may also explore positions in pediatrics, geriatrics, and home health care, each offering unique challenges and the chance to make a meaningful impact on patient lives. With South Carolina’s growing focus on healthcare innovation and quality of care, there is ample opportunity for professional development and advancement in this region. Whether working in urban centers like Charleston or in the picturesque rural areas, Registered Nurses are essential to ensuring the health and wellbeing of communities across the Palmetto State.

What Are Some Reasons a RN Professional Should Choose a Travel Job in South Carolina?

As a Registered Nurse considering a travel job, South Carolina offers a unique blend of vibrant culture, stunning landscapes, and a warm climate that makes it an ideal destination. With mild winters and long, sunny summers, the state’s weather provides the perfect backdrop for exploring its charming cities like Charleston, renowned for its rich history and beautiful architecture, and Greenville, celebrated for its revitalized downtown and outdoor activities. South Carolina boasts beautiful beaches along the coast, from the lively Ocean City and serene Pawleys Island to the iconic Hilton Head Island, perfect for unwinding after a busy week. When you’re not caring for patients, you can immerse yourself in rich local cuisine, enjoy world-class golfing, or partake in numerous festivals celebrating the region’s distinctive culture. A travel nursing career in South Carolina not only enriches your professional experience but also invites you to enjoy all the diverse experiences this southern gem has to offer.

Top Cities in South Carolina with Travel Registered Nurse Jobs

AMN Healthcare currently has 17 travel Registered Nurse jobs in South Carolina. Be sure to check back daily for updates, or if you’re not finding what you’re looking for immediately, sign up for the AMN Passport App and we’ll connect you directly with a recruiter that can help expedite the process of finding your perfect opportunity.
View All Jobs in South Carolina

Highest Paying Jobs in Rock Hill

AMN Healthcare currently has travel Registered Nurse positions available in Rock Hill.
travel Exclusive Compact State
Registered Nurse – Cardiovascular
  • Rock Hill, South Carolina – 29732
  • 12 N,
  • December 29, 2025
  • 13 weeks
$2,021 to $2,228
Weekly Pay*
Common Diagnosis/Treatment: open heart surgery, neuro surgery, vascular surgery, trauma, and overflow medical # of Beds: 8 Nurse to Patient Ratio: 1:1, 2:1, 3:1 Charting: Cerner Scrub Color: Navy Blue Scrubs Areas of Float Support: MICU, SICU, other medical units with max of 4 patients Special Procedures: chest tube, swan, temp pacers, cordess, cardiac continuous output, JP drains, central lines, art lines, trach, peg, G/J tube
travel Exclusive Compact State
Registered Nurse – Cardiovascular
  • Rock Hill, South Carolina – 29732
  • 12 N,
  • December 29, 2025
  • 13 weeks
$2,021 to $2,228
Weekly Pay*
Common Diagnosis/Treatment: open heart surgery, neuro surgery, vascular surgery, trauma, and overflow medical # of Beds: 8 Nurse to Patient Ratio: 1:1, 2:1, 3:1 Charting: Cerner Scrub Color: Navy Blue Scrubs Areas of Float Support: MICU, SICU, other medical units with max of 4 patients Special Procedures: chest tube, swan, temp pacers, cordess, cardiac continuous output, JP drains, central lines, art lines, trach, peg, G/J tube
travel Exclusive Compact State
Registered Nurse – Perioperative Nurse – Operating Room
  • Rock Hill, South Carolina – 29732
  • 12 D,
  • December 8, 2025
  • 13 weeks
$1,933 to $2,130
Weekly Pay*
Common Diagnosis/Treatment: Surgical # of Beds: 15 Nurse Patient Ratio: 1-1 Charting: Cerner Scrub Color: Navy blue Areas of Float Support: Special Procedures: Surgical
travel Exclusive Compact State
Registered Nurse – Perioperative Nurse – Operating Room
  • Rock Hill, South Carolina – 29732
  • 12 D,
  • December 18, 2025
  • 13 weeks
$1,933 to $2,130
Weekly Pay*
Common Diagnosis/Treatment: Surgical # of Beds: 15 Nurse Patient Ratio: 1-1 Charting: Cerner Scrub Color: Navy blue Areas of Float Support: Special Procedures: Surgical
View all Jobs in Rock Hill

Highest Paying Jobs in Florence

AMN Healthcare currently has travel Registered Nurse positions available in Florence.
travel Compact State
Registered Nurse – Assisted Living Nurse – Long-Term Care
  • Florence, South Carolina – 29506
  • 12 N,
  • December 8, 2025
  • 13 weeks
$1,898 to $2,091
Weekly Pay*
At Select Specialty Hospital, our goal is to help patients with medically complex conditions continue their recovery so they can regain their quality of life. Physician-led, multidisciplinary care teams support that recovery by developing a customized treatment plan that helps patients breathe, eat, walk, talk and think again. 10 hospitals nationwide, 22,000 respiratory patients treated annually
travel Compact State
Registered Nurse – Assisted Living Nurse – Long-Term Care
  • Florence, South Carolina – 29506
  • 12 D,
  • December 8, 2025
$1,898 to $2,091
Weekly Pay*
At Select Specialty Hospital, our goal is to help patients with medically complex conditions continue their recovery so they can regain their quality of life. Physician-led, multidisciplinary care teams support that recovery by developing a customized treatment plan that helps patients breathe, eat, walk, talk and think again. 10 hospitals nationwide, 22,000 respiratory patients treated annually
travel Compact State
Registered Nurse – Assisted Living Nurse – Long-Term Care
  • Florence, South Carolina – 29506
  • 12 N,
  • December 18, 2025
  • 13 weeks
$1,739 to $1,917
Weekly Pay*
At Select Specialty Hospital, our goal is to help patients with medically complex conditions continue their recovery so they can regain their quality of life. Physician-led, multidisciplinary care teams support that recovery by developing a customized treatment plan that helps patients breathe, eat, walk, talk and think again. 10 hospitals nationwide, 22,000 respiratory patients treated annually
View all Jobs in Florence

Highest Paying Jobs in Charleston

AMN Healthcare currently has travel Registered Nurse positions available in Charleston.
travel Compact State
Registered Nurse – Medical Surgical
  • Charleston, South Carolina – 29401
  • 12 D,
  • December 15, 2025
  • 13 weeks
$1,495 to $1,647
Weekly Pay*
Join our team as a Travel Registered Nurse – Medical-Surgical (RN-MS) in Charleston, SC. This travel nursing opportunity allows you to work at a general medical and surgical hospital with a strong teaching culture, providing a collaborative environment for professional growth and exposure to a wide range of specialties. With over 170 physicians covering more than 70 specialty areas, you will work alongside experienced teams dedicated to delivering high-quality patient care and advancing medical education. The hospital’s commitment to excellence ensures a supportive setting for both new and seasoned clinicians to thrive and expand their skills. Charleston, SC is a coastal city known for its historic charm, beautiful beaches, and vibrant culinary scene. The city offers a blend of cultural attractions, outdoor activities, and a welcoming community, making it an ideal location for travel healthcare professionals seeking both professional and personal enrichment. AMN Healthcare provides excellent compensation, exclusive discounts and perks, dedicated recruiters and clinical support, and access to the AMN Passport mobile app for 24/7 career management. As a publicly traded company, AMN Healthcare upholds high ethical standards in all business practices. Apply now to join this Travel Registered Nurse – Medical-Surgical (RN-MS) assignment in Charleston, SC.
travel Compact State
Registered Nurse – Medical Surgical
  • Charleston, South Carolina – 29401
  • 12 N,
  • December 18, 2025
  • 13 weeks
$1,495 to $1,647
Weekly Pay*
Join our team as a Travel Registered Nurse – Medical-Surgical (RN-MS) in Charleston, SC. This travel nursing opportunity allows you to work at a general medical and surgical hospital with a strong teaching culture, providing a collaborative environment for professional growth and exposure to a wide range of specialties. With over 170 physicians covering more than 70 specialty areas, you will work alongside experienced teams dedicated to delivering high-quality patient care and advancing medical education. The hospital’s commitment to excellence ensures a supportive setting for both new and seasoned clinicians to thrive and expand their skills. Charleston, SC is a coastal city known for its historic charm, beautiful beaches, and vibrant culinary scene. The city offers a blend of cultural attractions, outdoor activities, and a welcoming community, making it an ideal location for travel healthcare professionals seeking both professional and personal enrichment. AMN Healthcare provides excellent compensation, exclusive discounts and perks, dedicated recruiters and clinical support, and access to the AMN Passport mobile app for 24/7 career management. As a publicly traded company, AMN Healthcare upholds high ethical standards in all business practices. Apply now to join this Travel Registered Nurse – Medical-Surgical (RN-MS) assignment in Charleston, SC.
View all Jobs in Charleston

Highest Paying Jobs in Fort Mill

AMN Healthcare currently has travel Registered Nurse positions available in Fort Mill.
travel Exclusive Compact State
Registered Nurse – Intensive Care – ICU
  • Fort Mill, South Carolina – 29715
  • 12 N,
  • December 18, 2025
  • 13 weeks
$1,774 to $1,955
Weekly Pay*
Common Diagnosis/Treatment: Critically ill patients # of Beds: 10 Nurse Patient Ratio: 2/3:1 Charting: Cerner Scrub Color: Navy blue Areas of Float Support: Intermediate, ED Special Procedures: Art lines, bedside bronch, central lines, chest tubes, intubation,
travel Exclusive Compact State
Registered Nurse – Medical Surgical
  • Fort Mill, South Carolina – 29715
  • 12 N,
  • December 29, 2025
  • 13 weeks
$1,545 to $1,703
Weekly Pay*
Common Diagnosis/Treatment: # of Beds: Nurse to Patient Ratio: Charting: Cerner Scrub Color: navy blue Areas of Float Support: Special Procedures
View all Jobs in Fort Mill

Discover RN Jobs in South Carolina with AMN Passport!

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Understanding Travel Registered Nurse Job Trends in South Carolina

As you explore the dynamic landscape of travel Registered Nurse jobs in South Carolina, we invite you to delve into the valuable statistics presented below. These insights detail average pay trends from the past three months, showcasing how earning potential has evolved. Additionally, you’ll find comprehensive data on salaries from the last year, including average, minimum, and maximum pay rates. This information is vital for making informed career decisions and understanding your worth in the ever-changing healthcare job market.

Furthermore, the charts provide a breakdown of the types of healthcare facilities throughout the U.S. that are actively seeking professionals in Medical Surgical, Telemetry, and Emergency Room positions. By accessing these statistics, you can gain a clearer picture of the opportunities available to you and the facilities that align best with your career goals. Empower yourself with this knowledge, and navigate your journey in the travel nursing industry with confidence!

Salary Range

Salary Trends

Jobs by Facility types

Frequently Asked Questions about Travel RN Jobs near South Carolina

What is the average pay for a Travel RN job in South Carolina?

The average weekly pay for a Travel Registered Nurse job in South Carolina is $1,853, based on 727 jobs as of December 4, 2025.

What is the highest weekly pay for a Travel Registered Nurse job in South Carolina?

Based on 727 recent jobs, the highest weekly pay for a Travel Registered Nurse job in South Carolina is $3,146, working in Progressive Care Unit, as of December 4, 2025.

What types of experience are most commonly required for a Travel Registered Nurse job in South Carolina?

Most travel Registered Nurse positions in South Carolina typically require at least one to two years of clinical experience in a relevant specialty, such as emergency, critical care, or medical surgical nursing. Additionally, candidates often need active state licensure and may be required to demonstrate proficiency in electronic health record systems.

What types of job opportunities are typically available for RN Travel positions in South Carolina?

Registered Nurse opportunities in South Carolina encompass Rapid Response, Per Diem, and Travel positions. These roles offer adaptable work arrangements, allowing professionals to choose options that align with their career goals, lifestyle, and level of experience.

What types of healthcare facilities in South Carolina typically offer Travel positions for Registered Nurse professionals?

In South Carolina, travel positions for Registered Nurse professionals are commonly found in hospitals, particularly in urban areas, as well as in specialized clinics and urgent care facilities. Additionally, long-term care facilities and rehabilitation centers often seek traveling nurses to meet fluctuating patient demands.

What types of specialties are common for a Registered Nurse professional working a Travel job in South Carolina?

Common specialties for a Registered Nurse working a travel job in South Carolina include critical care, emergency room, and surgical nursing. Many travel nurses also find opportunities in pediatrics and telemetry units due to the demand in various healthcare facilities. Additionally, the state’s flexibility in different healthcare settings allows for roles in home health and rehabilitation. Overall, diverse specialties are sought after, reflecting the state’s varied healthcare needs.

What are some keys reasons a Travel Registered Nurse professional might consider seeking a Medical Surgical, Telemetry, and Emergency Room job in South Carolina?

A travel Registered Nurse may be drawn to South Carolina for its increasing demand for healthcare professionals in areas like Medical Surgical, Telemetry, and Emergency Rooms, offering diverse experiences and competitive pay. Additionally, the state’s rich culture, beautiful landscapes, and historical sites provide a unique backdrop for both professional growth and personal enjoyment.

What are some most popular cities in South Carolina a Travel RN professionals would prefer to work and live?

Popular cities in South Carolina for travel Registered Nurse professionals include Charleston, known for its historic charm and vibrant healthcare community, and Greenville, which offers a growing job market and beautiful natural surroundings. Additionally, Columbia, the state capital, provides diverse opportunities in various medical facilities and a lively cultural scene. These cities strike a balance between professional growth and quality of life, making them appealing choices for nursing professionals.

What important factors should a Travel Registered Nurse professional consider when evaluating a new position in Medical Surgical, Telemetry, and Emergency Room in South Carolina?

When evaluating a new position in South Carolina, travel Registered Nurses should consider the state’s licensing requirements, including any necessary endorsements or compact agreements. Additionally, they should assess the quality of healthcare facilities, as well as the support and resources available in their chosen location. It’s also important to weigh factors like living costs, local amenities, and the overall work-life balance.

Which South Carolina Cities Offer Job Opportunities for Registered Nurse Professionals?

South Carolina is a vibrant state boasting a range of picturesque cities ideal for Registered Nurses specializing in Medical Surgical, Telemetry, and Emergency Room services. Rock Hill, Hilton Head Island, Florence, Charleston, and Myrtle Beach each present their distinctive advantages, combining rewarding job opportunities with appealing lifestyles that cater to both work and leisure. Here’s what you can expect when considering these locations for your next nursing adventure.

In Rock Hill, Registered Nurses can anticipate weekly pay ranging from $1,376 to $2,951, making it a financially attractive option. The cost of living in Rock Hill is relatively low compared to national averages, allowing for a comfortable lifestyle. With a variety of housing options, including charming neighborhoods and modern apartments, it’s a great place to settle. The work environment is supportive, with state-of-the-art medical facilities that offer strong teamwork dynamics. Rock Hill enjoys a mild climate, perfect for those who love outdoor activities like hiking and biking along the nearby trails, and the city is just a short drive from the culturally rich atmosphere of Charlotte, North Carolina.

On Hilton Head Island, where weekly pay can range from $828 to $2,738, working as a nurse in this stunning coastal paradise is a dream for many. Despite higher costs of living, the island’s breathtaking scenery and leisurely lifestyle compensate for the price tag. Housing options vary from oceanfront condos to charming cottages, creating a variety of choices for different budgets. The work environment in area hospitals and clinics is highly collaborative, allowing nurses to thrive and grow in their roles. With year-round warm weather, you can enjoy an array of recreational activities, including golfing, water sports, and dining at world-class restaurants, making it a picturesque locale for both work and play.

Florence offers competitive salary ranges for Registered Nurses, from $1,341 to $2,547 per week, with a cost of living that is well below the national average. This southern city provides affordable housing options, perfect for those looking to make the most out of their earnings. Its healthcare facilities deliver a nurturing work environment that values professional growth and development, making it a great choice for dedicated nurses. Florence experiences a subtropical climate that ensures warm summers and mild winters, allowing for ample outdoor adventures and community gatherings. The city hosts various events and festivals throughout the year that offer a delightful taste of southern charm and community spirit.

In Charleston, the pay range for Registered Nurses is between $1,440 and $2,514 per week. While the cost of living is higher than some other South Carolina cities, the rich history and vibrant culture more than justify it. Housing ranges from historic homes to modern apartments, ensuring that there’s something for everyone. The collaborative atmosphere within Charleston’s medical facilities supports nurses in delivering high-quality care. Nurses can bask in the city’s pleasant climate, with plenty of sunshine throughout the year. Charleston is brimming with activities from exploring its historic districts to diving into its renowned culinary scene, creating a lifestyle that combines professional satisfaction and abundant leisure activities.

Myrtle Beach offers an exciting pay scale for Registered Nurses, ranging from $1,436 to $2,519 per week, against a backdrop of moderately priced living costs. The city is known for its diverse housing options, including beachfront properties and cozy inland residences. The work atmosphere in local hospitals ensures a tight-knit community where nurses are supported and appreciated. With a warm coastal climate that attracts visitors year-round, Myrtle Beach allows for a leisure-filled lifestyle that includes a wide array of entertainment and recreational activities—from sun-soaked beaches to water parks and golf courses. This vibrant city is perfect for those who appreciate a dynamic lifestyle filled with fun and festivities, making your nursing career an enjoyable experience on and off the clock.

Discover Healthcare Facilities in South Carolina That Hire Registered Nurse Professionals

AMN Healthcare proudly presents a selection of top-tier healthcare facilities in South Carolina known for their robust history of hiring Registered Nurse professionals for travel positions in Medical Surgical, Telemetry, and Emergency Room settings. These organizations not only provide dynamic opportunities for dedicated nurses but also foster an environment where professionals can thrive and advance their careers in the ever-evolving nursing landscape.

East Cooper Medical Center
Shifts
8 E, 10 D, 12 D, and 12 N
Job Durations
1 wks, 12 wks, 13 wks, and 14 wks
Address
2000 Hospital Dr
Mount Pleasant, SC 29464
Nearby Neighborhoods
Parish Place (29465), Point Pleasant (29465), Wando Estates (29413), Somerset Point (29413), Hickory Shadows (29465)
Bon Secours St. Francis Downtown (Simplify)
Shifts
8 D, 8 E, 10 D, 12 D, 12 E, and 12 N
Job Durations
12 wks and 13 wks
Departments
Cardiovascular ICU Registered Nurse, Cardiovascular Operating Room Registered Nurse, Cardiovascular Operating Room Surgical Technologist, Cardiovascular Operating Room Surgical Technology, CVOR Surgical First Assist Nursing, First Assist Registered Nurse, First Assist Surgical Technology, First Assist Surgical Technology, First Assist Surgical Technology Nursing, First Assist Surgical Technology Nursing, Operating Room RN, and OR Surgical First Assist Nursing
Address
1 Saint Francis Dr
Greenville, SC 29601
Nearby Neighborhoods
University Ridge Homes (29601), Boyce Lawn (29616), Mountain View Homes (29601), Alta Vista (29603), Roosevelt Heights (29603)
McLeod Health Cheraw (FKA: Chesterfield General Hospital)
Shifts
8 D, 10 D, 12 D, and 12 N
Job Durations
13 wks
Address
711 CHESTERFIELD HWY.
Cheraw, SC 29520
* Estimate of payments is intended for informational purposes and includes hourly wages, as well as reimbursements for meal & incidental expenses and housing expenses incurred on behalf of the Company. Please speak with a recruiter for additional details.