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First Assist Travel Nursing Jobs in St. Louis, MO for RNs

More on Travel Jobs for First Assist RN in St. Louis

At AMN Healthcare, we proudly offer exciting travel First Assist job opportunities in St. Louis, designed specifically for dedicated Nursing professionals seeking adventure and career growth. With 40 years of experience as a staffing leader, we support over 10,000 healthcare workers each year, providing them with personalized guidance that empowers them throughout their careers. Our commitment to excellence means you’ll receive tailored support and resources to ensure your travel experience is both fulfilling and rewarding. Join us and explore the benefits of working with a trusted partner in travel nursing as you take your skills to new places and make a meaningful impact in diverse healthcare settings.

Explore Top-Paying First Assist Registered Nurse Job in St. Louis with AMN Healthcare

Here is the top paying First Assist RN job currently available in St. Louis, Missouri:

AMN Healthcare currently has 1 First Assist Registered Nurse job available in St. Louis, with start dates as early as 12/8/25. As of December 4, 2025, the average weekly pay for a First Assist Registered Nurse in St. Louis was $2,327, with the range in pay between $2,214 and $2,440.

If St. Louis isn’t your only option, we also have First Assist Registered Nurse jobs nearby in O Fallon (15.7 miles), Carbondale (81.9 miles) and Cape Girardeau (98.5 miles). Or, if you’re looking for cities with the largest variety of First Assist Registered Nurse jobs available currently, you should try Denver (1 jobs), Longview (1 jobs), Columbia (1 jobs), Tulare (0 jobs), and Indianapolis (0 jobs).

If you’re interested, just Apply Now and we’ll match you with a recruiter for more personalized service!

Research First Assist RN Job Trends in St. Louis

If you’re a First Assist Registered Nurse curious about Travel job trends in St. Louis, MO, AMN Healthcare has successfully filled 2 similar positions in the area, providing insight into the opportunities you could expect. These previously filled roles offered competitive pay, with an average weekly rate of $2,008 and a range from $1,608 to $2,440 per week, showcasing the strong earning potential for professionals in this field.

Positions were located in key zip codes, including 63141, at reputable facilities such as Mercy Hospital St Louis. These placements reflect the high demand for skilled First Assist Registered Nurses in St. Louis’s thriving healthcare landscape. With AMN Healthcare, you can count on access to similar roles tailored to your expertise and career goals. Explore how you can join this network of professionals and take the next step in your career today!

Here’s a look at some of the most recently filled First Assist RN positions in St. Louis, giving you a glimpse into the competitive pay rates and opportunities available.

  • First Assist Registered Nurse making $2,440 per week filled on 11/21/25
  • First Assist Registered Nurse making $1,772 per week filled on 10/15/25
  • First Assist Registered Nurse making $2,762 per week filled on 5/1/25

What Types of Work and Facilities Can First Assist Registered Nurses Expect in St. Louis, MO?

As a First Assist Registered Nurse in St. Louis, Missouri, you can expect to find a diverse range of opportunities across various healthcare settings, including esteemed hospitals, surgical centers, and specialty clinics. In this vital role, you will collaborate closely with surgeons in the operating room, providing critical assistance during complex procedures while ensuring patient safety and comfort. Facilities such as Barnes-Jewish Hospital and SSM Health St. Louis University Hospital are renowned for their comprehensive surgical programs, offering a dynamic environment where you can enhance your skills in multiple specialties, from orthopedics to cardiac surgery. Additionally, outpatient surgical centers present opportunities for a more focused role in pre-operative and post-operative care, allowing you to work in an efficient and patient-centered setting. The thriving healthcare landscape in St. Louis not only offers competitive compensation and benefits but also a supportive community for professional growth and development.

Why Should First Assist Registered Nurses Consider Working in St. Louis, Missouri

As a First Assist Registered Nurse considering travel opportunities, St. Louis, Missouri offers an exciting blend of vibrant urban life and rich cultural experiences. The city’s cost of living is generally lower than that of larger metropolises, making it financially attractive for healthcare professionals. St. Louis boasts a temperate climate, characterized by warm summers and mild winters, perfect for year-round outdoor activities. Popular neighborhoods like the historic Soulard, known for its charming architecture and lively farmers’ market, and the artsy Grand Center, home to theaters and galleries, provide diverse living options. Additionally, the city is famous for its iconic Gateway Arch, delicious barbecue cuisine, and attractions like the St. Louis Zoo and Botanical Garden, ensuring that your downtime is filled with engaging pursuits and opportunities to explore.

Search Travel First Assist Registered Nurse Jobs in St. Louis as of December 4, 2025

Discover exciting travel First Assist Registered Nurse opportunities waiting for you in St. Louis! Browse through the listings below to find the perfect position that aligns with your career goals and passion for nursing.

travel Compact State
Registered Nurse – First Assistant
  • Saint Louis, Missouri – 63141
  • 12 D,
  • December 8, 2025
  • 13 weeks
$2,214 to $2,440
Weekly Pay*
EMR-EPIC Scrub Color – Black
travel Compact State
Registered Nurse – First Assistant
  • Columbia, Missouri – 65201
    Distance from St. Louis: 117 miles
  • 10 D,
  • December 13, 2025
  • 13 weeks
$2,663 to $2,935
Weekly Pay*
Start your next assignment as a Travel RN CVOR First Assistant in Columbia, MO, and join a dynamic cardiovascular operating room at the facility. You will work in a hospital recognized for its commitment to safety, quality care, and continuous learning. To qualify, you need an active RN license, 1-2 years of recent cardiovascular operating room (CVOR) experience, and current perioperative nursing certifications. Experience with electronic medical records (EMR) is required. Strong clinical skills, attention to detail, and the ability to collaborate in a fast-paced surgical environment are essential. Recommended skills include prior travel nursing experience, adaptability, and a dedication to delivering compassionate, high-quality patient care. The unit values professional growth and offers opportunities for recognition and ongoing education. AMN Healthcare provides excellent compensation, exclusive discounts and perks, dedicated recruiters, and the AMN Passport app for 24/7 support. Apply now to join this Travel RN CVOR First Assistant assignment in Columbia, MO, and advance your career with AMN Healthcare.
travel Compact State
Registered Nurse – First Assistant
  • Madisonville, Kentucky – 42431
    Distance from St. Louis: 172 miles
  • 8 D,
  • December 18, 2025
  • 13 weeks
$2,514 to $2,771
Weekly Pay*
travel Compact State
Registered Nurse – First Assistant
  • Madisonville, Kentucky – 42431
    Distance from St. Louis: 172 miles
  • 8 D,
  • December 18, 2025
  • 13 weeks
$2,514 to $2,771
Weekly Pay*
travel Compact State
Registered Nurse – First Assistant
  • Cincinnati, Ohio – 45255
    Distance from St. Louis: 308 miles
  • 12 D,
  • December 18, 2025
  • 13 weeks
$2,557 to $2,818
Weekly Pay*
At Mercy Health — Anderson Hospital, located on Cincinnati’s East Side, we understand the value of exceeding your and your family’s needs in the healing process. That’s why we foster a patient and family-centered atmosphere, backed, of course, by award-winning care.
travel Compact State
Registered Nurse – First Assistant
  • Longview, Texas – 75601
    Distance from St. Louis: 494 miles
  • 8 D,
  • March 2, 2026
  • 13 weeks
$2,008 to $2,212
Weekly Pay*
travel Compact State
Registered Nurse – First Assistant
  • Wilson, North Carolina – 27893
    Distance from St. Louis: 705 miles
  • 8 D,
  • December 8, 2025
$1,686 to $1,858
Weekly Pay*
As a part of Duke LifePoint Healthcare, our community hospital is being supported with more resources than ever before. Duke LifePoint combines Duke University Health System’s unparalleled expertise in clinical excellence, quality and patient safety with LifePoint Health’s financial resources and extensive operational experience – making our hospital even stronger.
travel Exclusive Compact State
Registered Nurse – First Assistant
  • Denver, Colorado – 80205
    Distance from St. Louis: 795 miles
  • 12 D,
  • December 18, 2025
  • 13 weeks
$1,995 to $2,198
Weekly Pay*
travel Compact State
Registered Nurse – First Assistant
  • Calais, Maine – 04619
    Distance from St. Louis: 1,257 miles
  • 12 D,
  • December 15, 2025
  • 13 weeks
$2,133 to $2,351
Weekly Pay*
Join our team as an Operating Room (OR) Registered Nurse (RN) – First Assist in Calais, ME. In this role, you will assist surgeons during operations, ensuring patient safety and optimal outcomes. The facility is known for its commitment to quality care and advanced medical services. You must have an active RN license, certification as a First Assist, and at least 2 years of OR experience. Proficiency with electronic medical records (EMR) is required. Experience in a similar setting is preferred. AMN Healthcare offers excellent compensation, discounts, and perks. You will have access to dedicated recruiters and a clinical team, as well as the AMN Passport mobile app for 24/7 support. Apply now to join this Travel OR RN – First Assist assignment in Calais, ME.
travel
Registered Nurse – First Assistant
  • Hermiston, Oregon – 97838
    Distance from St. Louis: 1,559 miles
  • 12 D,
  • December 15, 2025
  • 13 weeks
$2,403 to $2,648
Weekly Pay*
Join our team as a Registered Nurse First Assist (RNFA) in Hermiston, OR. In this role, you will deliver safe, effective, and quality patient-family centered care in the operating room and throughout perioperative services. As a Perioperative RNFA, you will primarily function as the RN first assistant during operative and other invasive procedures, supporting patients across all populations. You are responsible for care delivery in the operating room and other perioperative areas, following your scope of practice, credentials, privileges, experience, and education. Required qualifications include experience in perioperative nursing and RNFA certification, along with strong clinical skills and the ability to work collaboratively with the surgical team. AMN Healthcare offers excellent compensation, exclusive discounts and perks, dedicated recruiters, a clinical support team, and access to the AMN Passport mobile app for 24/7 career support. Apply now to join this Travel RN First Assist assignment in Hermiston, OR.
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Stats for Travel First Assist Registered Nurse Jobs in St. Louis

As a valuable resource for healthcare professionals, we understand the importance of having access to essential data when considering travel First Assist Registered Nurse (RN) opportunities in St. Louis. Below, you’ll find comprehensive statistics that provide insight into the current job market, including average pay trends over the last three months. This information can help you make well-informed decisions about your career path and understand the financial landscape of travel nursing in this vibrant city.

In addition to pay trends, the data also highlights the average, minimum, and maximum salaries for positions over the past year, giving you a clear picture of potential earnings. Furthermore, you’ll discover details about the various healthcare facilities in St. Louis that are actively seeking First Assist RNs, enabling you to assess the types and numbers of opportunities available. We encourage you to leverage this data to gain a deeper understanding of the job market and take the next step in your travel nursing journey with confidence.

Salary Range

Jobs by Facility types

Frequently Asked Questions about Travel First Assist RN Jobs near St. Louis, MO

What is the average pay for a First Assist RN Travel job in St. Louis, Missouri?

The average pay for a First Assist Registered Nurse Travel job in St. Louis, Missouri is approximately $2,115 per week. This data was last updated on December 4, 2025.

What is the highest pay typically available for a First Assist Registered Nurse Travel job in St. Louis, Missouri?

The highest pay typically available for a First Assist Registered Nurse Travel job in St. Louis, Missouri is $2,440 per week. This is based on data last updated on December 4, 2025.

What types of experience are required or preferred for a First Assist Registered Nurse Travel job in St. Louis?

For a First Assist Registered Nurse travel job in St. Louis, Missouri, candidates typically need to have experience in perioperative nursing and demonstrate proficiency in surgical procedures, particularly in assisting surgeons. Preferred qualifications often include advanced certifications in specialty areas such as surgical nursing or prior travel nursing experience for adaptability in various clinical settings.

What types of jobs are typically available for First Assist RN Travel positions in St. Louis?

There are a variety of First Assist RN positions in St. Louis, including Travel jobs. These options provide flexibility depending on your career preferences and lifestyle.

What types of facilities offer First Assist Registered Nurse Travel jobs in St. Louis?

First Assist Registered Nurse travel jobs in St. Louis, Missouri are typically found in hospitals, particularly those with surgical departments and trauma centers. Additionally, specialty clinics and outpatient surgery centers may also offer such positions, catering to a diverse range of surgical procedures.

What kinds of work shifts are typically offered for First Assist Registered Nurse Travel jobs in St. Louis?

For First Assist Registered Nurse Travel jobs in St. Louis, typical work shifts include 12 D, 8 N, 12 N, and 10 N. These shift options provide flexibility depending on your preferences and availability.

What kinds of contract durations are typically offered for First Assist Registered Nurse Travel jobs in St. Louis, MO?

For First Assist Registered Nurse Travel jobs in St. Louis, MO, typical contract durations range from 13 weeks. These flexible contract lengths allow you to choose an assignment that best fits your career goals and lifestyle preferences.

What kinds of benefits and support from an employer should a First Assist RN ask for when looking for a Travel job in St. Louis, Missouri?

A First Assist Registered Nurse should inquire about comprehensive benefits such as housing stipends or accommodations, travel reimbursements, and health insurance options to ensure their needs are met while working in St. Louis. Additionally, access to continuing education, mentorship, and resources for professional growth can enhance their experience and effectiveness in the role.

What are some top reasons a Travel First Assist Registered Nurse would have for looking for a job in St. Louis, Missouri?

A travel First Assist Registered Nurse might seek a job in St. Louis for its vibrant healthcare industry, which offers numerous opportunities for professional growth and diverse patient experiences. Additionally, the city’s rich cultural heritage and attractions provide an appealing backdrop for both work and leisure.

What are some popular areas in or near St. Louis, Missouri a Travel First Assist Registered Nurse would want to work and live in?

Some popular neighborhoods in St. Louis that a travel First Assist Registered Nurse might consider are the Central West End, known for its vibrant cultural scene and proximity to medical centers, as well as Clayton, which offers a more suburban feel with excellent amenities and schools. Additionally, the Soulard area provides a lively atmosphere with historic charm and diverse dining options. Each of these neighborhoods provides a unique living experience while being conveniently located near healthcare facilities.

What things should a Travel First Assist RN look for in a new position?

A travel First Assist Registered Nurse should look for positions that offer competitive compensation and benefits to ensure that their financial and professional needs are met. It’s also important to assess the support and resources available at the facility, as well as the opportunities for continuing education and professional growth. Additionally, understanding the work environment and team dynamics can greatly impact job satisfaction and performance in a new role.

Similar Cities to St. Louis, Missouri, for First Assist Registered Nurses: Opportunities, Lifestyle, and Pay Comparisons

Kansas City, Missouri, which is located about 250 miles west of St. Louis, shares many similarities, particularly in terms of cost of living and job opportunities for healthcare professionals. The average salary for a First Assist Registered Nurse in Kansas City is comparable to that in St. Louis, with a slightly lower cost of living making it an attractive option for nurses. Housing options vary from suburban neighborhoods to vibrant urban settings, providing a wide range of styles and prices. The city’s work environment tends to foster collaboration among healthcare teams, enhancing job satisfaction. With its barbecue culture, arts scene, and numerous parks, Kansas City offers a lively lifestyle filled with activities for residents to enjoy.

Another comparable city is Memphis, Tennessee, positioned to the south of St. Louis. Memphis features a cost of living that’s often lower than that of St. Louis, making it a viable alternative for First Assist Registered Nurses looking to maintain a comfortable lifestyle. Salaries for nurses in Memphis are competitive, and the healthcare industry is robust due to the presence of renowned hospitals and medical centers. The city is known for its rich musical heritage and a variety of cultural experiences, from the vibrant Beale Street to the National Civil Rights Museum. The warm, humid climate, with hot summers and mild winters, creates a different atmosphere compared to St. Louis but appeals to those who enjoy outdoor activities year-round.

Indianapolis, Indiana, is another city that presents a comparable environment for First Assist Registered Nurses. The pay scale for nurses in Indianapolis is generally in line with that found in St. Louis, and the cost of living is relatively low, which contributes to a favorable quality of life. The housing market offers diverse options, from affordable suburbs to upscale downtown lofts. As a city known for its major sports events and a rich cultural landscape, Indianapolis encourages a fulfilling lifestyle filled with recreational activities. Additionally, the climate features four distinct seasons, appealing to those who appreciate experiencing varying weather conditions throughout the year.

Columbus, Ohio, embodies many of the same qualities as St. Louis for First Assist Registered Nurses. The average nurse salary in Columbus closely mirrors that of St. Louis, and the cost of living is manageable, allowing for a comfortable lifestyle. Housing options range from historic homes to modern apartments, catering to various preferences. Columbus is recognized for its vibrant arts and food scenes, plus numerous parks and outdoor spaces, making it an attractive city for those who value an active lifestyle. The climate is similar to that of St. Louis, with hot summers and cold winters, providing a familiar environment for those relocating from Missouri.

Finally, Nashville, Tennessee, has grown exponentially in recent years and is becoming a desirable location for healthcare professionals, including First Assist Registered Nurses. While salaries in Nashville are competitive with those in St. Louis, the cost of living has risen due to the city’s popularity; however, it still offers affordable housing outside the downtown core. Nashville’s dynamic atmosphere is enhanced by its music scene, as well as a wide array of restaurants and outdoor activities. The warm climate provides great opportunities for year-round outdoor enjoyment, making Nashville a vibrant place to live and work for those in the healthcare field.

Top St. Louis Healthcare Facilities Typically Hiring First Assist Registered Nurse Professionals for Travel Positions

St. Louis boasts a vibrant healthcare landscape that has consistently sought the expertise of First Assist Registered Nurse professionals for travel positions across various facilities. This demand not only highlights the city’s commitment to providing quality patient care but also presents an exciting opportunity for skilled nurses to make a meaningful impact while enjoying the rich culture and community that St. Louis has to offer.

Mercy Hospital St Louis
Shifts
8 D, 8 N, 10 D, 10 N, 12 D, 12 E, and 12 N
Job Durations
11 wks, 13 wks, 18 wks, 20 wks, and 26 wks
Address
615 S New Ballas Rd
Saint Louis, MO 63141
Nearby Neighborhoods
Rock Springs (63110), Southwest Garden (63139), Cabanne Place (63112), Botanical Heights (63110)
* Estimate of payments is intended for informational purposes and includes hourly wages, as well as reimbursements for meal & incidental expenses and housing expenses incurred on behalf of the Company. Please speak with a recruiter for additional details.