At AMN Healthcare, we are excited to present exceptional per diem Medical Surgical job opportunities in the vibrant city of San Antonio for dedicated Nursing professionals. With over 40 years of experience as a staffing leader, we proudly support more than 10,000 healthcare workers annually, ensuring they find roles that align with their skills and career aspirations. Our commitment to personalized guidance empowers Medical Surgical RNs to navigate their professional journeys with confidence, providing them with the resources and support needed to excel in their careers. If you are seeking flexible per diem positions that allow you to make a significant impact in patient care while enjoying a work-life balance, AMN Healthcare is here to help you unlock your potential and embrace new opportunities.
Here are some of the highest paying Medical Surgical RN jobs currently available in San Antonio, Texas:
AMN Healthcare currently has 2 Medical Surgical Registered Nurse jobs available in San Antonio, with start dates as early as 12/18/25. As of December 4, 2025, the average hourly pay for a Medical Surgical RN in San Antonio was $34, with the range in pay between $33 and $36.
If San Antonio isn’t your only option, we also have Medical Surgical Registered Nurse jobs nearby in Austin (73.6 miles), Humble (197.9 miles) and Fort Worth (238.4 miles). Or, if you’re looking for cities with the largest variety of Medical Surgical Registered Nurse jobs available currently, you should try Osseo (8 jobs), Tucson (8 jobs), Denver (7 jobs), New York City (6 jobs), and Ocala (4 jobs).
If you’re interested, just Apply Now and we’ll match you with a recruiter for more personalized service!
If you’re a Medical Surgical RN curious about Per Diem job trends in San Antonio, TX, AMN Healthcare has successfully filled 4 similar positions in the area, providing insight into the opportunities you could expect. These previously filled roles offered competitive pay, with an average hourly rate of $33 and a range from $31 to $34 per hour, showcasing the strong earning potential for professionals in this field.
Positions were located in key zip codes, including 78229, 78258, and 78240, at reputable facilities such as St Lukes Baptist Hospital and North Central Baptist Hospital. These placements reflect the high demand for skilled Medical Surgical RNs in San Antonio’s thriving healthcare landscape. With AMN Healthcare, you can count on access to similar roles tailored to your expertise and career goals. Explore how you can join this network of professionals and take the next step in your career today!
Here’s a look at some of the most recently filled Medical Surgical RN positions in San Antonio, giving you a glimpse into the competitive pay rates and opportunities available.
As a Registered Nurse specializing in Medical Surgical care in San Antonio, Texas, you can expect a dynamic and rewarding career across a variety of healthcare settings. San Antonio boasts a diverse array of facilities, including community hospitals, teaching hospitals, and specialty clinics that cater to a broad spectrum of patient needs, ranging from post-operative care to chronic illness management. In these environments, you will be responsible for providing direct patient care, administering medications, and monitoring vital signs while collaborating closely with multidisciplinary teams to ensure comprehensive patient treatment plans. Additionally, San Antonio’s vibrant healthcare scene is characterized by a commitment to professional development, offering opportunities for advancement and specialization in areas such as wound care, telemetry, and palliative care, making it an ideal location for Medical Surgical RNs to thrive in their careers.
As a Medical Surgical RN considering a per diem position in San Antonio, Texas, you’ll find an array of compelling reasons to make this vibrant city your home. San Antonio boasts a rich cultural heritage, renowned for its picturesque River Walk, historic missions, and festive events like Fiesta—making it a lively backdrop for both work and play. The climate is typically warm, with mild winters and hot summers, perfect for outdoor enthusiasts looking to explore the nearby picturesque Hill Country. Popular neighborhoods such as Alamo Heights offer charming homes and proximity to top-rated schools and restaurants, while the bustling Pearl District features trendy shops and a thriving food scene. With a lower cost of living compared to many other metropolitan areas, plus a supportive healthcare community, working per diem with AMN Healthcare allows you to embrace San Antonio’s unique charm and enjoy a flexible work-life balance filled with delicious Tex-Mex cuisine and exciting local festivals.
Explore a range of exciting per diem Medical Surgical Registered Nurse positions available in San Antonio, where you can find the flexibility and work-life balance you desire. Dive into our listings below and discover the perfect opportunity that aligns with your skills and career goals!
As you explore the dynamic landscape of per diem Medical Surgical Registered Nurse opportunities in San Antonio, the following statistics are designed to provide you with valuable insights into the job market. You’ll discover trends in average pay over the last three months, offering a glimpse into how compensation has evolved. Additionally, we’ve compiled data on the average, minimum, and maximum pay rates for nursing positions over the past year, enabling you to gauge your earning potential in this vibrant healthcare environment.
Beyond salary information, the charts also highlight the diversity of healthcare facilities in San Antonio that are currently hiring. From renowned hospitals to specialized clinics, these statistics will help you understand where demand is highest and what types of roles might best align with your skills and career goals. We encourage you to leverage this data as a strategic tool in your job search, ensuring you make informed decisions as you navigate your path in the healthcare sector.
Candidates for a per diem Medical Surgical Registered Nurse position in San Antonio are typically required to have a valid Texas RN license along with relevant clinical experience in med-surg settings. While not always mandatory, additional certifications such as BLS or ACLS are often preferred to enhance a candidate’s qualifications.
Medical Surgical Registered Nurse per diem jobs in San Antonio, Texas, are typically found in hospitals, outpatient clinics, and rehabilitation centers. These facilities often seek flexible staffing options to accommodate varying patient care needs.
When seeking a per diem position in San Antonio, a Medical Surgical RN should inquire about flexible scheduling options to accommodate their personal commitments and varying patient care needs. Additionally, benefits such as competitive pay rates, access to continuing education resources, and support for maintaining nursing certifications can enhance job satisfaction and professional growth.
A per diem Medical Surgical RN might seek a job in San Antonio for its growing healthcare industry and competitive pay rates, along with the city’s rich cultural diversity and vibrant community life. Additionally, the warm climate and numerous recreational opportunities can enhance their quality of life outside of work.
Popular neighborhoods in San Antonio for a per diem Medical Surgical RN include Alamo Heights, known for its upscale homes and vibrant cultural scene, and the Pearl District, which offers a trendy atmosphere with shops and eateries. The Southtown area also attracts medical professionals due to its artsy vibe and proximity to downtown hospitals. Each of these areas provides convenient access to healthcare facilities and a lively community environment.
A per diem Medical Surgical RN should seek a position that offers flexibility in scheduling to accommodate their availability and personal commitments. It’s also important to consider the hospital’s culture and support systems, as a collaborative and positive work environment can significantly enhance job satisfaction. Additionally, reviewing the level of orientation and training provided can help ensure they feel prepared to handle the demands of different units.
At AMN Healthcare, we understand the dynamic landscape of healthcare employment, particularly for Medical Surgical Registered Nurses (MS RNs) seeking flexible work arrangements. Our latest list of recent job placements for per diem MS RN positions in San Antonio, Texas, provides valuable insights into the types of opportunities currently available in this bustling market. By examining these placements, prospective candidates can gain a clearer understanding of the qualifications, responsibilities, and environments that characterize MS roles, empowering them to make informed decisions about their career paths in this vital field. Whether you’re a seasoned professional or new to the profession, this curated list serves as a helpful resource in navigating your next career move.
Phoenix, Arizona, shares several similarities with San Antonio for Medical Surgical RNs considering job opportunities. Both cities feature a warm, arid climate that offers plenty of sunshine year-round, which can be appealing for those who enjoy outdoor activities. The pay range for RNs in Phoenix is competitive, generally aligning closely with what is seen in San Antonio, while the cost of living is slightly higher but manageable, particularly for those who choose to live in suburban areas. The job market for healthcare professionals is robust, with numerous hospitals and healthcare facilities available. Additionally, Phoenix offers a vibrant lifestyle with a growing arts scene, excellent dining options, and nearby natural attractions like the Grand Canyon and numerous hiking trails.
Another city that mimics San Antonio’s characteristics for Medical Surgical RNs is Jacksonville, Florida. Jacksonville boasts a similar climate with mild winters and hot summers, making it ideal for those who appreciate warm weather. The cost of living in Jacksonville is reasonably comparable to San Antonio, with a range of housing options from urban apartments to suburban single-family homes. The pay for RNs is competitive, and the job market is particularly strong with various healthcare systems continually seeking nursing staff. Jacksonville also has a rich cultural landscape, including beautiful beaches, parks, and recreational activities, along with a lower overall population density, which can be appealing for a more laid-back lifestyle.
Dallas, Texas, is another city worth considering for Medical Surgical RNs who want an experience similar to that of San Antonio. Though Dallas has a higher cost of living than San Antonio, it offers a wider range of job opportunities with competitive salaries for nurses. The healthcare industry is booming in Dallas, with many large hospitals and specialty clinics that consistently seek skilled nursing professionals. The climate features hot summers and mild winters, making it similar in warmth, and the vibrant lifestyle offers an array of entertainment options, from professional sports teams to an extensive music scene and diverse culinary offerings. Despite the hustle and bustle of a larger city, many neighborhoods in Dallas maintain a family-friendly atmosphere.
Charlotte, North Carolina, provides an alternative city with a quality of life and job market that may appeal to Medical Surgical RNs looking for a San Antonio vibe. Charlotte’s healthcare sector is expanding rapidly, with several renowned hospitals and healthcare providers operating in the area, resulting in a good salary range comparable to RNs in San Antonio. The cost of living is slightly higher but remains affordable relative to many major U.S. cities. With a temperate climate that features four distinct seasons—mild winters and hot summers—Charlotte has much to offer in terms of outdoor activities. The city’s vibrant culture, including music festivals and a growing food scene, promotes a lively lifestyle that is increasingly attractive to newcomers.
Lastly, Nashville, Tennessee, presents an attractive alternative for Medical Surgical RNs. The pay for RNs in Nashville is competitive and, while the cost of living has been on the rise, many areas still offer affordable housing options compared to other major urban centers. Nashville is home to a robust healthcare economy, hosting numerous hospitals and healthcare facilities known for their innovative practices. The city enjoys a mild climate, with warm summers and cool winters, which complements its inviting atmosphere. Beyond work, Nashville’s lively music scene, arts culture, and recreational opportunities—including nearby parks and lakes—contribute to a dynamic lifestyle that attracts many young professionals and families alike.
San Antonio boasts a robust healthcare landscape that frequently seeks skilled Medical Surgical Registered Nurses for per diem positions, offering flexibility and rewarding experiences. From renowned hospitals to specialized clinics, these facilities provide ample opportunities for nursing professionals to advance their careers while meeting the diverse needs of patients in this thriving community.