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Emergency Room Per Diem Nursing Jobs South Carolina for RNs

Learn More About Per Diem Opportunities in Emergency Room Registered Nurse in South Carolina

At AMN Healthcare, we understand the unique demands and rewards of being an Emergency Room Registered Nurse, which is why we are proud to offer flexible per diem job opportunities in South Carolina tailored to meet your lifestyle and career goals. With over 40 years of experience as a leader in healthcare staffing, we support more than 10,000 nursing professionals annually, providing personalized guidance and resources that empower you throughout your career journey. Our commitment to excellence ensures that you have access to rewarding positions that fit your expertise and aspirations, allowing you to make a meaningful impact in the critical setting of emergency care. Join us and experience the AMN difference as you take the next step in your nursing career.

Explore Top Emergency Room Registered Nurse Jobs in South Carolina with Flexible Opportunities at AMN Healthcare

Check out these top-paying Emergency Room RN job openings currently available in South Carolina:

At AMN Healthcare, we currently have 2 Per Diem Emergency Room Registered Nurse job opportunities available across Short Term Acute Care Hospital (2 jobs) in South Carolina, offering competitive hourly pay ranging from $35 to $38, with an average of $36 per hour.

Our job openings are located in multiple zip codes, including 29732, with flexible start dates on 12/18/25 (2 jobs), ensuring that you can find the right fit for your schedule and career goals.

If you’re looking for opportunities in high-demand areas, the cities in South Carolina with the most job openings include Rock Hill (2 jobs). If you’re ready to take the next step, simply click Apply Now, and we’ll connect you with a recruiter for tailored support!

Where Can an ER RN Work in South Carolina and What Can They Expect?

As a Registered Nurse specializing in Emergency Room (ER) care in South Carolina, you can expect a dynamic and rewarding career across a variety of healthcare settings, including hospitals, urgent care centers, and trauma facilities. South Carolina boasts a mix of urban and rural environments, allowing ER RNs to work in large metropolitan hospitals equipped with advanced technology and specialized care teams, as well as smaller community hospitals that provide essential emergency services to local populations. In these roles, you will be responsible for triaging patients, providing critical care during acute emergencies, collaborating with interdisciplinary teams, and implementing life-saving interventions in high-pressure situations. Additionally, opportunities abound for professional development and specialization, making South Carolina an attractive state for those looking to advance their careers while making a significant impact on patient outcomes in emergency medicine.

Why Should Emergency Room RNs Consider a Per Diem Job in South Carolina?

As an Emergency Room RN considering a per diem role in South Carolina, you’ll find both professional and personal rewards in this vibrant state. South Carolina boasts a mild climate with warm summers and temperate winters, providing year-round opportunities for outdoor activities. The state features lively cities like Charleston, known for its rich history and charming architecture, and Greenville, where a rapidly growing downtown offers a mix of arts, dining, and cultural festivals. Living here also means easy access to stunning beaches, such as Myrtle Beach, and the picturesque Blue Ridge Mountains for hiking enthusiasts. Furthermore, as a per diem nurse, you can enjoy the flexibility to balance work and leisure, making it easy to explore the local cuisine, partake in seasonal events, or simply relax in the natural beauty that South Carolina offers.

Top Cities in South Carolina with Per Diem Emergency Room RN Jobs

AMN Healthcare currently has 2 per diem ER RN jobs in South Carolina and 114 nationwide. Be sure to check back daily for updates, or if you’re not finding what you’re looking for immediately, sign up for the AMN Passport App and we’ll connect you directly with a recruiter that can help expedite the process of finding your perfect opportunity.

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Highest Paying Emergency Room RN Jobs in Rock Hill, SC

AMN Healthcare currently has per diem Emergency Room positions available in Rock Hill.
per diem
Emergency Room Nurse (ER RN)
  • Rock Hill, South Carolina – 29732
  • 12 N,
  • December 18, 2025
$35 to $38
Hourly Pay*
ER RN’s treat patients in emergency situations where they are experiencing trauma or injury. They quickly recognize life-threatening problems and are trained to help solve them on the spot. ER RN’s treat a variety of conditions from sore throats to heart attacks for patients of all ages and backgrounds. They will stabilize patients experiencing trauma and help minimize pain. ER RN’s work in hospital emergency rooms and departments (ER and ED), ambulances, helicopters, urgent care centers, sports arenas, and more. ER’s and hospitals are given a Trauma Rating I-III based upon the kinds of resources available in a trauma center, and the number of patients admitted yearly. Level I is the highest (capable of providing total care for every aspect of injury) and Level III (Level-3) being the lowest. Education/Requirements:
  • Bachelor of Science in Nursing (BSN): 4-Year Education 
  • Associates Degree in Nursing (ADN): 2-Year Education 
  • You must earn an ADN or BSN degree and pass the NCLEX to apply for a license as a RN. 
  • RN‘s can only work with an active state license.
*Per Diem Shifts Available  Recent Experience Required.
per diem
Emergency Room Nurse (ER RN)
  • Rock Hill, South Carolina – 29732
  • 12 D,
  • December 18, 2025
$35 to $38
Hourly Pay*
ER RN’s treat patients in emergency situations where they are experiencing trauma or injury. They quickly recognize life-threatening problems and are trained to help solve them on the spot. ER RN’s treat a variety of conditions from sore throats to heart attacks for patients of all ages and backgrounds. They will stabilize patients experiencing trauma and help minimize pain. ER RN’s work in hospital emergency rooms and departments (ER and ED), ambulances, helicopters, urgent care centers, sports arenas, and more. ER’s and hospitals are given a Trauma Rating I-III based upon the kinds of resources available in a trauma center, and the number of patients admitted yearly. Level I is the highest (capable of providing total care for every aspect of injury) and Level III (Level-3) being the lowest. Education/Requirements:
  • Bachelor of Science in Nursing (BSN): 4-Year Education 
  • Associates Degree in Nursing (ADN): 2-Year Education 
  • You must earn an ADN or BSN degree and pass the NCLEX to apply for a license as a RN. 
  • RN‘s can only work with an active state license.
*Per Diem Shifts Available  Recent Experience Required.
View all Jobs in Rock Hill, SC

Highest Paying Emergency Room RN Jobs in Lithonia, GA

AMN Healthcare currently has per diem Emergency Room positions available in Lithonia.
per diem
Emergency Room Nurse (ER RN)
  • Lithonia, Georgia – 30058
  • 12 E,
  • December 18, 2025
$34 to $37
Hourly Pay*
ER RN’s treat patients in emergency situations where they are experiencing trauma or injury. They quickly recognize life-threatening problems and are trained to help solve them on the spot. ER RN’s treat a variety of conditions from sore throats to heart attacks for patients of all ages and backgrounds. They will stabilize patients experiencing trauma and help minimize pain. ER RN’s work in hospital emergency rooms and departments (ER and ED), ambulances, helicopters, urgent care centers, sports arenas, and more. ER’s and hospitals are given a Trauma Rating I-III based upon the kinds of resources available in a trauma center, and the number of patients admitted yearly. Level I is the highest (capable of providing total care for every aspect of injury) and Level III (Level-3) being the lowest. Education/Requirements:
  • Bachelor of Science in Nursing (BSN): 4-Year Education 
  • Associates Degree in Nursing (ADN): 2-Year Education 
  • You must earn an ADN or BSN degree and pass the NCLEX to apply for a license as a RN. 
  • RN‘s can only work with an active state license.
***Float as needed within skillset Years of Experience: 2 BLS, ACLS, NIHSS. PALS
View all Jobs in Lithonia, GA

Highest Paying Emergency Room RN Jobs in Decatur, GA

AMN Healthcare currently has per diem Emergency Room positions available in Decatur.
per diem
Emergency Room Nurse (ER RN)
  • Decatur, Georgia – 30033
  • 12 E,
  • December 18, 2025
$34 to $37
Hourly Pay*
ER RN’s treat patients in emergency situations where they are experiencing trauma or injury. They quickly recognize life-threatening problems and are trained to help solve them on the spot. ER RN’s treat a variety of conditions from sore throats to heart attacks for patients of all ages and backgrounds. They will stabilize patients experiencing trauma and help minimize pain. ER RN’s work in hospital emergency rooms and departments (ER and ED), ambulances, helicopters, urgent care centers, sports arenas, and more. ER’s and hospitals are given a Trauma Rating I-III based upon the kinds of resources available in a trauma center, and the number of patients admitted yearly. Level I is the highest (capable of providing total care for every aspect of injury) and Level III (Level-3) being the lowest. Education/Requirements:
  • Bachelor of Science in Nursing (BSN): 4-Year Education 
  • Associates Degree in Nursing (ADN): 2-Year Education 
  • You must earn an ADN or BSN degree and pass the NCLEX to apply for a license as a RN. 
  • RN‘s can only work with an active state license.
***Float as needed within skillset Years of Experience: 2 BLS, ACLS, NIHSS. PALS
View all Jobs in Decatur, GA

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Insights into Per Diem Emergency Room Registered Nurse Job Trends in South Carolina

In today’s dynamic healthcare landscape, understanding the job market is essential for any professional looking to navigate their career effectively. Below, you will find a comprehensive set of statistics detailing per diem Emergency Room RN jobs available in South Carolina. This data provides valuable insights into average pay trends over the past three months, alongside a detailed breakdown of the average, minimum, and maximum pay observed in the last year. By analyzing these figures, you can gain a clearer perspective on compensation expectations and make informed decisions about your career trajectory.

Additionally, we’ve included information regarding the count and types of healthcare facilities across the U.S. that are actively seeking qualified RNs. This overview not only highlights the demand for skilled professionals in various settings but also serves as a benchmark for your own job search. We encourage you to leverage this data as a strategic tool to better understand the opportunities available in the job market and position yourself for success in your nursing career.

Salary Range

Jobs by Facility types

Frequently Asked Questions about Per Diem Emergency Room Registered Nurse Jobs near South Carolina

How much does a Per Diem Emergency Room RN earn in South Carolina on average?

As of December 4, 2025 the average hourly pay for a Per Diem Emergency Room RN in South Carolina is $36.

What is the highest salary offered for a Emergency Room RN Per Diem job in South Carolina?

As of December 4, 2025, the highest hourly pay for a per diem Emergency Room RN job in South Carolina is $38.

What types of experience are often expected for an ER Per Diem job in South Carolina?

For an Emergency Room (ER) job in South Carolina, candidates are typically expected to have relevant clinical experience, such as working in urgent care, critical care, or directly in emergency medicine. Additional certifications like Advanced Cardiac Life Support (ACLS) and a strong ability to thrive in high-pressure situations can also enhance a candidate’s qualifications.

What job opportunities are typically available for Emergency Room Registered Nurse per diem positions in SC?

Emergency Room positions in South Carolina include Per Diem roles. These options provide flexibility for professionals seeking different work arrangements based on their preferences and experience.

What types of facilities typically hire Emergency Room RN Per Diem jobs in South Carolina?

Emergency Room per diem jobs in South Carolina are typically offered by hospitals, including community hospitals and larger healthcare systems, as well as urgent care centers that require flexible staffing to accommodate varying patient volumes. These facilities often seek qualified professionals to help manage unpredictable emergency care needs on an as-needed basis.

Which work shifts are typically offered for ER per diem jobs in South Carolina?

Typical work shifts offered for per diem ER positions in South Carolina include 12 N and 12 D shifts. These options provide flexibility to accommodate different scheduling preferences.

What kinds of benefits from an employer should an ER RN look for when looking for a Per Diem job in South Carolina?

When considering a per diem job in South Carolina, it’s important to look for employers that offer flexible scheduling, as this allows for better work-life balance. Competitive pay rates are also crucial, as they can significantly impact overall earnings especially in a per diem position where hours may vary. Additionally, opportunities for professional development, such as training or continuing education support, can enhance your skills and career prospects. Lastly, benefits like access to health insurance and retirement plans, even on a per diem basis, can be essential for securing your financial well-being.

What are some top reasons a Per Diem Emergency Room RN would have for looking for a job in South Carolina?

A per diem might seek a job in South Carolina for its diverse healthcare opportunities and growing demand for temporary staff in various medical facilities. Additionally, the state’s pleasant climate and rich culture can be appealing factors for professionals looking for a rewarding work-life balance.

What are some most popular cities in South Carolina a Per Diem Emergency Room RN would want to work and live in?

Some of the most popular cities in South Carolina for a per diem worker to consider are Charleston, known for its rich history and vibrant culture, as well as Greenville, which boasts a growing economy and scenic beauty. Myrtle Beach is also an attractive option due to its beautiful coastline and recreational opportunities. Each city offers unique amenities and lifestyles that cater to diverse preferences.

What things should a Per Diem ER RN look for in a new position?

When considering a new per diem position, it’s important to evaluate the flexibility of the schedule and how well it aligns with your availability. Additionally, look for competitive pay rates and benefits that support your financial needs. Lastly, the workplace environment and the culture of the organization should resonate with your professional values and personal work style.

Which Cities in South Carolina Offer the Best ER RN Job Opportunities?

South Carolina is home to vibrant cities that offer ample opportunities for Emergency Room Registered Nurses (RNs) looking to advance their careers while enjoying a fulfilling lifestyle. Among these cities, Rock Hill stands out not only for its job openings but also for the unique blend of community, culture, and convenience it offers to healthcare professionals.

In Rock Hill, the average pay for an Emergency Room RN ranges from $1,406 to $1,510 per week, making it an attractive location for nursing professionals looking to maximize their earning potential. The cost of living in Rock Hill is notably lower than the national average, allowing residents to enjoy a comfortable lifestyle without a hefty financial burden. This affordability is reflected in the variety of housing options available, from charming single-family homes to modern apartment complexes, ensuring that nurses can find a place that suits their personal preferences and budget.

The work environment in Rock Hill fosters collaboration and professional growth within the healthcare field, emphasizing both patient care and staff support. Hospitals and healthcare facilities in the area are equipped with the latest technology and offer ongoing training programs, ensuring that Emergency Room RNs are well-prepared to handle the fast-paced demands of their roles. Furthermore, Rock Hill’s strategic location near Charlotte, North Carolina, provides additional career opportunities and easy access to a larger metropolitan market.

Climate plays a significant role in the lifestyle one can expect in Rock Hill. With a temperate climate characterized by warm summers and mild winters, residents can enjoy outdoor activities year-round. The city boasts a variety of parks, trails, and green spaces, making it a wonderful place for nature enthusiasts and families alike.

Beyond its professional and residential appeal, Rock Hill offers a vibrant community filled with cultural attractions and recreational activities. From local festivals and farmers’ markets to art galleries and sports events, there are countless ways for Emergency Room RNs to unwind after a rewarding day at work. The city’s growing food scene, complemented by a rich history and a welcoming neighborhood atmosphere, makes Rock Hill not just a place to work, but a place to call home.

Discover Healthcare Facilities in South Carolina That Hire Emergency Room RN Professionals

Discover the diverse range of healthcare facilities in South Carolina that consistently seek skilled Emergency Room RN nursing professionals for per diem opportunities. From bustling urban hospitals to tranquil rural clinics, these organizations are committed to providing high-quality care while offering flexible scheduling options tailored to the needs of dedicated nurses.

MUSC Health – Florence Medical Center
Departments
Cardiac Anesthesiology, Emergency Room Nurse Practitioner, Emergency Room Nurse Practitioner, Internal Medicine Nurse Practitioner, Nocturnist, and Radiology
Address
805 PAMPLICO HWY., #. 100550
Florence, SC 29505
Nearby Neighborhoods
Nob Hill (29501), Siesta Village (29501), Parkwood (29501), Fairlane Estates (29501), Crownland Estates (29501)
McLeod Health Cheraw (FKA: Chesterfield General Hospital)
Shifts
8 D, 10 D, 12 D, and 12 N
Job Durations
13 wks
Address
711 CHESTERFIELD HWY.
Cheraw, SC 29520
* Estimate of payments is intended for informational purposes and includes hourly wages, as well as reimbursements for meal & incidental expenses and housing expenses incurred on behalf of the Company. Please speak with a recruiter for additional details.