AMN Healthcare, a recognized leader in healthcare staffing for over 40 years, is excited to invite Nursing professionals to explore exceptional travel Medical Surgical job opportunities in Sioux Falls. With a commitment to supporting over 10,000 healthcare workers annually, we understand the unique demands of nursing professionals and offer personalized guidance tailored to your career aspirations. Our dedicated team will help you navigate the dynamic landscape of travel nursing, ensuring you find the perfect fit for your skills and lifestyle. Join us at AMN Healthcare, where your expertise is valued, and embark on an enriching journey that enhances your nursing career while experiencing new environments and making a difference in the lives of patients.
Here are some of the highest paying Medical Surgical RN jobs currently available in Sioux Falls, South Dakota:
AMN Healthcare currently has 3 Medical Surgical Registered Nurse jobs available in Sioux Falls, with start dates as early as 12/7/25. As of December 4, 2025, the average weekly pay for a Medical Surgical RN in Sioux Falls was $1,624, with the range in pay between $1,392 and $1,787.
If Sioux Falls isn’t your only option, we also have Medical Surgical Registered Nurse jobs nearby in Tyler (57.7 miles), North Sioux City (71.5 miles) and Sioux City (74.1 miles). Or, if you’re looking for cities with the largest variety of Medical Surgical Registered Nurse jobs available currently, you should try Richmond (22 jobs), Englewood (21 jobs), Nashville (21 jobs), Atlanta (15 jobs), and Salem (13 jobs).
If you’re interested, just Apply Now and we’ll match you with a recruiter for more personalized service!
If you’re a Medical Surgical RN curious about Travel job trends in Sioux Falls, SD, AMN Healthcare has successfully filled 63 similar positions in the area, providing insight into the opportunities you could expect. These previously filled roles offered competitive pay, with an average weekly rate of $1,786 and a range from $1,452 to $2,574 per week, showcasing the strong earning potential for professionals in this field.
Positions were located in key zip codes, including 57105 and 57108, at reputable facilities such as Avera McKennan Hospital & University Health Center. These placements reflect the high demand for skilled Medical Surgical RNs in Sioux Falls’s thriving healthcare landscape. With AMN Healthcare, you can count on access to similar roles tailored to your expertise and career goals. Explore how you can join this network of professionals and take the next step in your career today!
Here’s a look at some of the most recently filled Medical Surgical RN positions in Sioux Falls, giving you a glimpse into the competitive pay rates and opportunities available.
Sioux Falls, South Dakota offers a diverse range of opportunities for Registered Nurses specializing in Medical Surgical care, with several top-tier facilities available to support their career growth. Nurses in this role can expect to work in acute care hospitals, where they will provide comprehensive patient assessments, coordinate multidisciplinary care, and administer medications and treatments in fast-paced environments. Additionally, skilled nursing facilities and outpatient clinics in the area focus on post-operative and rehabilitation care, allowing RNs to utilize their expertise in managing complex medical conditions. With a strong emphasis on patient-centered care, those working as Medical Surgical RNs in Sioux Falls will play a critical role in improving patient outcomes while benefiting from a supportive community and numerous professional development opportunities.
As a Medical Surgical RN considering a travel opportunity in Sioux Falls, South Dakota, you’ll find a unique blend of professional growth and lifestyle benefits that make this experience worthwhile. Sioux Falls offers a lower cost of living compared to many urban centers while providing a friendly, welcoming community ripe with cultural experiences. The weather features four distinct seasons, with warm summers perfect for outdoor adventures and snowy winters that charm the holiday season. Popular neighborhoods such as the bustling Downtown area and the family-friendly neighborhoods of Cherry Rock and McKennan Park provide safe and enjoyable living environments. In your downtime, you can explore the stunning landscapes of Falls Park, enjoy local arts at the Sioux Falls Theatre Company, take a scenic bike ride along the Sioux River Greenway, or indulge in the local culinary scene, ensuring your travel assignment is not just a job, but a memorable adventure.
Explore a range of exciting Travel Medical Surgical Registered Nurse positions available in Sioux Falls, where you can advance your career while experiencing the vibrant culture of this thriving city. Dive into our curated list of job opportunities below to find your perfect fit and take the next step in your healthcare journey with AMN Healthcare!
In today’s dynamic healthcare landscape, understanding the job market is essential for professionals seeking opportunities that align with their skills and career goals. The following statistics provide a comprehensive overview of the current state of travel Medical Surgical Registered Nurse positions in Sioux Falls. Here, you’ll find valuable insights into average pay trends over the past three months, allowing you to gauge how compensation is evolving in the region. Additionally, data on the average, minimum, and maximum pay for these roles over the last year offers a clearer picture of earning potential.
Beyond compensation, it’s crucial to familiarize yourself with the healthcare facilities in Sioux Falls that are actively hiring. The information presented here highlights the variety and count of establishments offering opportunities, giving you a better understanding of where you might apply your expertise. We encourage you to leverage this data to navigate the job market more effectively and uncover the right fit for your next career move in this vibrant Midwestern community.
Most Medical Surgical Registered Nurse travel positions in Sioux Falls typically require at least one year of clinical experience in a medical-surgical setting, along with current state licensure. Preferred candidates often have experience with electronic health records and may benefit from certifications in basic life support or advanced cardiac life support.
Medical Surgical Registered Nurse travel jobs in Sioux Falls, South Dakota, are typically found in hospitals and healthcare systems that provide a variety of inpatient services. These facilities often include general acute care hospitals, specialty hospitals, and medical centers that focus on surgical and post-operative care.
For Medical Surgical Registered Nurse Travel jobs in Sioux Falls, SD, typical contract durations range from 1-8 weeks, 9-12 weeks, and 13 weeks. These flexible contract lengths allow you to choose an assignment that best fits your career goals and lifestyle preferences.
When looking for a travel job as a Medical Surgical RN in Sioux Falls, South Dakota, it’s essential to ask for comprehensive benefits such as housing assistance, travel reimbursement, and health insurance coverage. Additionally, inquiring about orientation programs and support for licensure in South Dakota can significantly impact job satisfaction and ease the transition into a new role.
Travel Medical Surgical RNs may be drawn to Sioux Falls for its growing healthcare facilities and the opportunity to work in a community that values patient care. Additionally, the city offers a vibrant culture and outdoor recreational activities, making it an attractive place to live and work.
Some popular neighborhoods in Sioux Falls for a travel Medical Surgical RN include the downtown area, which offers a vibrant atmosphere with various restaurants and entertainment options, and the southwest part of the city, known for its family-friendly environment and parks. The Falls Park area is also appealing, providing scenic views and recreational activities. Each of these neighborhoods combines convenience with a welcoming community feel, making them ideal for both work and living.
A travel Medical Surgical RN should look for positions that offer competitive pay and benefits, ensuring fair compensation for their skills and experience. It’s also important to consider the facility’s reputation, support for travelers, and the specific patient population to ensure a good fit for one’s expertise. Additionally, opportunities for professional growth and learning in a new environment can enhance the overall experience.
At AMN Healthcare, we are committed to connecting talented healthcare professionals with meaningful opportunities across the nation. Our recent list of travel Medical Surgical Registered Nurse (MS RN) job placements in Sioux Falls, South Dakota, serves as a valuable resource for RNs seeking to understand the types of positions typically available in this vibrant community. By exploring these job placements, you can gain insight into the specific skills and qualifications in demand, as well as the diverse settings where MS RNs can make a significant impact. Whether you’re considering your next career move or simply curious about the evolving landscape of healthcare roles, our comprehensive job placements can provide a clearer picture of the exciting possibilities ahead.
One city that mirrors Sioux Falls in the context of a Medical Surgical RN position is Rapid City, South Dakota. Much like Sioux Falls, Rapid City offers a relatively low cost of living, making it an attractive option for healthcare professionals. The housing market is affordable, with a mix of single-family homes, apartments, and townhouses available. The climate is similar, characterized by cold winters and warm summers, and the outdoor lifestyle is enhanced by proximity to the Black Hills and Mount Rushmore, providing ample opportunities for hiking and exploring nature. The working environment in healthcare facilities often emphasizes community-oriented care, fostering a supportive atmosphere for nurses.
Another comparable city is Fargo, North Dakota, which is known for its burgeoning healthcare sector. Fargo’s median salary for Medical Surgical RNs aligns closely with that of Sioux Falls, benefiting from a cost of living that is also quite manageable. Housing options range from historic homes to modern developments, allowing for diverse living arrangements. The climate is somewhat more severe, with cold winters, though it has a vibrant cultural scene, including arts, festivals, and community events that contribute to a lively lifestyle. Healthcare institutions in Fargo often offer competitive benefits and encourage professional development, providing an appealing work environment for nursing professionals.
Moving south, Little Rock, Arkansas, presents another alternative. While the climate is milder compared to Sioux Falls, it still experiences seasonal changes, contributing to diverse outdoor activities year-round. The cost of living in Little Rock is lower than the national average, with affordable housing options, including apartments and family homes. For Medical Surgical RNs, pay scales are competitive, with plenty of available positions due to the city’s growing healthcare network. The local culture is rich with Southern hospitality, delicious cuisine, and an array of recreational and historical sites, making it an engaging place to live and work.
Springfield, Missouri, is also a viable option resembling Sioux Falls in various aspects. The city boasts an affordable cost of living, with housing options that cater to different lifestyles, from urban apartments to suburban homes. The median salary range for Medical Surgical RNs is competitive, reflecting the growth of the healthcare industry within the region. Springfield experiences a temperate climate, ideal for enjoying outdoor activities in the Ozarks. The city also prides itself on a strong community feel, with numerous parks, cultural events, and local attractions that contribute to a fulfilling lifestyle for professionals and families alike.
Lastly, consider Grand Island, Nebraska, which offers a smaller-town charm similar to Sioux Falls. Known for its reasonable cost of living and housing prices, Grand Island presents a practical option for Medical Surgical RNs. The city has an average salary range comparable to Sioux Falls, with a growing network of healthcare employers looking to hire qualified nursing staff. The climate features distinct seasons, and the area’s recreational offerings, including parks and nearby natural attractions, support an active lifestyle. With a community-focused environment and a commitment to healthcare quality, Grand Island is appealing for nursing professionals seeking a balance of work and personal fulfillment.
Sioux Falls, known for its vibrant healthcare community, is home to a variety of facilities that consistently seek skilled Medical Surgical Registered Nurses for travel positions. Our comprehensive list highlights these reputable institutions, showcasing opportunities for experienced professionals to deliver quality care while experiencing the charm of SD’s largest city.