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Medical Surgical Per Diem Nursing Jobs South Carolina for RNs

Learn More About Per Diem Opportunities in Medical Surgical RN in South Carolina

At AMN Healthcare, we understand the unique needs of Medical Surgical RNs seeking per diem opportunities in South Carolina, and with over 40 years as a staffing leader, we are committed to connecting you with rewarding positions that fit your lifestyle and professional goals. Every year, we support more than 10,000 healthcare workers, providing personalized guidance to ensure that your career path is aligned with your aspirations. By partnering with AMN Healthcare, you gain access to a wide range of per diem job openings that not only offer flexibility but also allow you to make a meaningful impact in patient care. Let us help you navigate your nursing career and find the perfect opportunity that suits your expertise and availability.

Explore Top Medical Surgical RN Jobs in South Carolina with Flexible Opportunities at AMN Healthcare

Check out these top-paying Medical Surgical Registered Nurse job openings currently available in South Carolina:

At AMN Healthcare, we currently have 3 Per Diem Medical Surgical RN job opportunities available across Short Term Acute Care Hospital (3 jobs) in South Carolina, offering competitive hourly pay ranging from $33 to $38, with an average of $36 per hour.

Our job openings are located in multiple zip codes, including 29732 and 29464, with flexible start dates on 12/18/25 (3 jobs), ensuring that you can find the right fit for your schedule and career goals.

If you’re looking for opportunities in high-demand areas, the cities in South Carolina with the most job openings include Rock Hill (2 jobs). If you’re ready to take the next step, simply click Apply Now, and we’ll connect you with a recruiter for tailored support!

Where Can a Medical Surgical RN Work in South Carolina and What Can They Expect?

As a Medical Surgical RN in South Carolina, you can expect to find rewarding opportunities across a variety of healthcare settings, including bustling community hospitals, specialized surgical centers, and long-term acute care facilities. Your role will involve providing comprehensive patient care, monitoring vital signs, managing post-operative recovery, and collaborating with a multidisciplinary team to ensure optimal patient outcomes. Whether you’re working in a scenic coastal town or a vibrant city like Charleston or Columbia, you’ll engage with diverse patient populations, enhancing your clinical skills while contributing to the health and well-being of the community. With the increasing demand for healthcare services in the region, South Carolina offers a robust job market, allowing for flexibility in shifts and the potential for career advancement in both clinical and administrative pathways.

Why Should Medical Surgical RNs Consider a Per Diem Job in South Carolina?

As a Medical Surgical RN considering a per diem job in South Carolina, you’ll be delighted by the state’s blend of professional flexibility and vibrant lifestyle. South Carolina offers a mild climate year-round, with warm summers and mild winters, making it an ideal place for outdoor enthusiasts and those who enjoy a variety of recreational activities. Cities like Charleston, with its historic charm and waterfront views, and Greenville, known for its thriving arts scene and beautiful parks, provide a dynamic living environment. While working per diem, you’ll have the opportunity to explore the stunning beaches of the Lowcountry, hike in the Blue Ridge Mountains, or indulge in the state’s renowned cuisine, including delightful Southern barbecue and seafood. This unique combination of a fulfilling job, rich culture, and diverse landscapes makes South Carolina an attractive option for those seeking both professional growth and a vibrant lifestyle.

Top Cities in South Carolina with Per Diem Medical Surgical Registered Nurse Jobs

AMN Healthcare currently has 3 per diem Medical Surgical RN jobs in South Carolina and 114 nationwide. Be sure to check back daily for updates, or if you’re not finding what you’re looking for immediately, sign up for the AMN Passport App and we’ll connect you directly with a recruiter that can help expedite the process of finding your perfect opportunity.

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Highest Paying Medical Surgical RN Jobs in Rock Hill, SC

AMN Healthcare currently has per diem Medical Surgical positions available in Rock Hill.
per diem
Medical Surgical Nurse (MS RN)
  • Rock Hill, South Carolina – 29732
  • 12 D,
  • December 18, 2025
$35 to $38
Hourly Pay*
MS RN's care for adult patients who are acutely ill with a wide variety of medical problems and diseases or are recovering from surgery. Med Surg unit of a facility is where ill patients go to recover before being discharged. They handle large patient loads, juggle multiple patient populations, and adapt to the ever-changing face of nursing care. Although most MS RN's work in the Med Surg unit of hospitals, they can work in a variety of settings includes camps, clinics, schools, and ambulatory care centers.Education/Requirements:
  • Bachelor of Science in Nursing (BSN): 4-Year Education 
  • Associates Degree in Nursing (ADN): 2-Year Education 
  • You must earn an ADN or BSN degree and pass the NCLEX to apply for a license as a RN. 
  • RN‘s can only work with an active state license.
  • ACLS occasionally required
*Per Diem Shifts Available  Recent Experience Required.
per diem
Medical Surgical Nurse (MS RN)
  • Rock Hill, South Carolina – 29732
  • 12 N,
  • December 18, 2025
$35 to $38
Hourly Pay*
MS RN's care for adult patients who are acutely ill with a wide variety of medical problems and diseases or are recovering from surgery. Med Surg unit of a facility is where ill patients go to recover before being discharged. They handle large patient loads, juggle multiple patient populations, and adapt to the ever-changing face of nursing care. Although most MS RN's work in the Med Surg unit of hospitals, they can work in a variety of settings includes camps, clinics, schools, and ambulatory care centers.Education/Requirements:
  • Bachelor of Science in Nursing (BSN): 4-Year Education 
  • Associates Degree in Nursing (ADN): 2-Year Education 
  • You must earn an ADN or BSN degree and pass the NCLEX to apply for a license as a RN. 
  • RN‘s can only work with an active state license.
  • ACLS occasionally required
*Per Diem Shifts Available  Recent Experience Required.
View all Jobs in Rock Hill, SC

Highest Paying Medical Surgical RN Jobs in Mount Pleasant, SC

AMN Healthcare currently has per diem Medical Surgical positions available in Mount Pleasant.
per diem Exclusive
Medical Surgical Nurse (MS RN)
  • Mount Pleasant, South Carolina – 29464
  • 12 N,
  • December 18, 2025
$33 to $36
Hourly Pay*
MS RN's care for adult patients who are acutely ill with a wide variety of medical problems and diseases or are recovering from surgery. Med Surg unit of a facility is where ill patients go to recover before being discharged. They handle large patient loads, juggle multiple patient populations, and adapt to the ever-changing face of nursing care. Although most MS RN's work in the Med Surg unit of hospitals, they can work in a variety of settings includes camps, clinics, schools, and ambulatory care centers.Education/Requirements:
  • Bachelor of Science in Nursing (BSN): 4-Year Education 
  • Associates Degree in Nursing (ADN): 2-Year Education 
  • You must earn an ADN or BSN degree and pass the NCLEX to apply for a license as a RN. 
  • RN‘s can only work with an active state license.
  • ACLS occasionally required
*Per Diem Shifts Available  Recent Experience Required.
View all Jobs in Mount Pleasant, SC

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Insights into Per Diem Medical Surgical RN Job Trends in South Carolina

As you explore the dynamic landscape of per diem Medical Surgical Registered Nurse jobs in South Carolina, the following data provides invaluable insights into the current job market. With average pay trends tracked over the past three months, you’ll gain a clear understanding of how compensation is evolving. Additionally, the data reflects the average, minimum, and maximum pay for these positions over the last year, helping you to gauge what to expect and negotiate as you navigate your career path.

Moreover, the information detailing the count and types of healthcare facilities across the U.S. reveals the abundance of opportunities available to skilled professionals like you. By leveraging this data, you can make informed decisions about your next career move, whether you’re entering the workforce or seeking new challenges. Stay ahead of the curve and use these insights to enhance your understanding of the per diem nursing job market.

Salary Range

Jobs by Facility types

Frequently Asked Questions about Per Diem Medical Surgical RN Jobs near South Carolina

How much does a Per Diem Medical Surgical RN earn in South Carolina on average?

As of December 4, 2025 the average hourly pay for a Per Diem Medical Surgical RN in South Carolina is $36.

What is the highest salary offered for a Medical Surgical Registered Nurse Per Diem job in South Carolina?

As of December 4, 2025, the highest hourly pay for a per diem Medical Surgical RN job in South Carolina is $38.

What types of experience are often expected for an MS Per Diem job in South Carolina?

For a MS (Management Systems) job in South Carolina, experience with project management, systems analysis, and proficiency in relevant software tools is often required. Additionally, a background in data analytics and previous roles in team leadership can enhance a candidate’s attractiveness to potential employers.

What job opportunities are typically available for Medical Surgical RN per diem positions in SC?

Medical Surgical positions in South Carolina include Per Diem roles. These options provide flexibility for professionals seeking different work arrangements based on their preferences and experience.

What types of facilities typically hire Medical Surgical Registered Nurse Per Diem jobs in South Carolina?

Medical Surgical per diem jobs in South Carolina are typically available in hospitals, outpatient centers, and rehabilitation facilities. These roles often provide flexible scheduling for nurses to support patient care across various units.

Which work shifts are typically offered for MS per diem jobs in South Carolina?

Typical work shifts offered for per diem MS positions in South Carolina include 12 N and 12 D shifts. These options provide flexibility to accommodate different scheduling preferences.

What kinds of benefits from an employer should a Medical Surgical RN look for when looking for a Per Diem job in South Carolina?

When seeking a per diem job in South Carolina, it’s important to look for benefits that enhance job satisfaction and financial security. Employers that offer flexible scheduling can greatly accommodate personal commitments, making the role more manageable. Additionally, consider whether the company provides any form of health benefits, even on a per diem basis, like access to employee assistance programs or health insurance options. Other valuable offerings might include professional development opportunities and reimbursement for travel expenses, which can significantly impact overall job experience.

What are some top reasons a Per Diem Medical Surgical RN would have for looking for a job in South Carolina?

A per diem worker may seek a job in South Carolina for the state’s growing healthcare industry and diverse job opportunities in various sectors, offering flexibility and potential career growth. Additionally, the lower cost of living and pleasant climate could be attractive incentives for relocation.

What are some most popular cities in South Carolina a Per Diem Medical Surgical RN would want to work and live in?

Some of the most popular cities in South Carolina for a per diem worker to live and work include Charleston, known for its historic charm and vibrant culture, and Columbia, the state capital, which offers a mix of urban amenities and outdoor recreation. Greenville is also a notable choice, with a thriving downtown and a strong sense of community. Each of these cities provides unique opportunities and a quality lifestyle that makes them appealing.

What things should a Per Diem Medical Surgical RN look for in a new position?

A per diem should look for flexibility in scheduling to accommodate personal commitments and preferences, as well as competitive pay rates that reflect their skills and experience. It’s also important to consider the work environment and team dynamics to ensure a supportive atmosphere. Lastly, the opportunity for skill development and advancement can enhance long-term career satisfaction.

Which Cities in South Carolina Offer the Best Medical Surgical RN Job Opportunities?

For medical professionals seeking vibrant communities to advance their careers, Rock Hill and Mount Pleasant in South Carolina offer enticing job opportunities for Medical Surgical Registered Nurses. With their unique charms, competitive pay, and a supportive environment, these cities provide an excellent backdrop for both personal and professional growth.

Rock Hill, located just south of Charlotte, NC, offers an impressive weekly salary for Medical Surgical RNs, ranging from $1,406 to $1,510. The cost of living in Rock Hill is relatively affordable compared to many urban areas, allowing nurses to enjoy a comfortable lifestyle without financial strain. Housing options in the city are diverse, including single-family homes, townhouses, and apartments, catering to various preferences and budgets. The work environment in Rock Hill is bolstered by a sense of community and collaboration among healthcare professionals, which can be incredibly rewarding. With a mild climate featuring four distinct seasons, residents can enjoy outdoor activities year-round, from hiking in nearby parks to exploring local festivals and events that showcase the city’s rich history.

Mount Pleasant, situated near the picturesque coastline, presents a pay range for Medical Surgical RNs between $1,330 and $1,428 per week. This charming town not only offers a competitive salary but also boasts a cost of living that is higher than the national average, yet the quality of life is undeniably appealing. The housing market includes a mix of luxury waterfront homes, historic properties, and modern apartments, providing options for various lifestyles. The healthcare facilities in Mount Pleasant foster a collaborative and dynamic work environment, encouraging professional growth and development. Additionally, the coastal climate brings warm, sunny days perfect for exploring the nearby beaches, historic sites, and a vibrant culinary scene that epitomizes Southern charm, making it an ideal location for those who value a balanced lifestyle.

Both Rock Hill and Mount Pleasant represent excellent opportunities for Medical Surgical Registered Nurses looking to embark on a fulfilling journey in South Carolina. With competitive salaries, diverse housing options, supportive work environments, and a wealth of lifestyle activities, these cities promise not just a job but a rich experience filled with personal and professional growth. Whether drawn by the local history, the beautiful landscapes, or the promise of community, healthcare professionals will find that their next great adventure awaits in these welcoming cities.

Discover Healthcare Facilities in South Carolina That Hire Medical Surgical Registered Nurse Professionals

In South Carolina, a diverse array of healthcare facilities has consistently embraced the expertise of Medical Surgical Registered Nurses for per diem positions, offering flexible opportunities for those seeking to enhance their careers while making a meaningful impact in patient care. From bustling hospitals to specialized clinics, these institutions understand the invaluable role of skilled nursing professionals in delivering quality healthcare and maintaining positive patient outcomes.

East Cooper Medical Center
Shifts
8 E, 10 D, 12 D, and 12 N
Job Durations
1 wks, 12 wks, 13 wks, and 14 wks
Address
2000 Hospital Dr
Mount Pleasant, SC 29464
Nearby Neighborhoods
Parish Place (29465), Point Pleasant (29465), Wando Estates (29413), Somerset Point (29413), Hickory Shadows (29465)
McLeod Health Cheraw (FKA: Chesterfield General Hospital)
Shifts
8 D, 10 D, 12 D, and 12 N
Job Durations
13 wks
Address
711 CHESTERFIELD HWY.
Cheraw, SC 29520
* Estimate of payments is intended for informational purposes and includes hourly wages, as well as reimbursements for meal & incidental expenses and housing expenses incurred on behalf of the Company. Please speak with a recruiter for additional details.