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Permanent Nurse Practitioner Advanced Practice Jobs in South Carolina

Find Exciting Permanent Nurse Practitioner Jobs in South Carolina with AMN Healthcare

Are you a Nurse Practitioner Advanced Practice professional seeking permanent job opportunities in South Carolina? Look no further! AMN Healthcare is your gateway to a wide array of rewarding career options in the heart of South Carolina. With a total of 1 permanent Nurse Practitioner jobs currently available, our platform is your one-stop destination for your job search needs.

Competitive Salaries for Nurse Practitioner Professionals in South Carolina

When it comes to compensation, AMN Healthcare ensures that our opportunities are not just abundant but also lucrative. The pay rates for our current Nurse Practitioner Advanced Practice jobs in South Carolina range from $120k to $140k annually. Based on jobs placed in the last year, the average pay rate for Nurse Practitioner positions in was $130k per year. In fact, the average annual salary for Nurse Practitioner positions currently available as of Dec 04, 2025 stands at $130k per year.

Nurse Practitioner Salary Trends in South Carolina

We understand that staying informed about salary trends is essential when you’re considering your next career move. Based on historical data from the last year of posted Nurse Practitioner jobs in South Carolina, the average pay hovers around $130k per year. It’s worth noting that the highest paying job in South Carolina for a permanent Nurse Practitioner role in the last year reached $140k annually, highlighting the potential for growth in your career.

Flexible Start Dates in South Carolina to Suit Your Schedule

At AMN Healthcare, we prioritize your convenience. As of Dec 04, 2025, we offer Nurse Practitioner jobs in South Carolina with a range of starting dates, including Dec 18, 2025 (1 job). This flexibility allows you to plan your transition into a new position seamlessly, giving you the freedom to choose what works best for your schedule.

Diverse Facilities Hiring Nurse Practitioner Professionals in South Carolina

In South Carolina, the types of facilities offering permanent jobs for Nurse Practitioner Advanced Practices are diverse. Whether you prefer to work in Physician Group (2 jobs) facilities, AMN Healthcare has you covered.

Don’t miss out on these exceptional career opportunities! Your dream job awaits!

Top Cities in South Carolina with Permanent Nurse Practitioner Jobs

AMN Healthcare currently has 1 permanent Nurse Practitioner positions available in the state of South Carolina. Search the most recent jobs below, or click the button below to view all jobs.

Highest Paying Jobs in South Carolina

AMN Healthcare currently has permanent Nurse Practitioner positions available in South Carolina.
permanent
Advanced Practice Provider (Nurse Practitioner / Physician Assistant)
  • December 18, 2025
$120k to $140k
Yearly Pay*
A respected, physician-led oncology group in Hilton Head, SC, is seeking a Board-Certified Nurse Practitioner or Physician Assistant to join its growing outpatient team. This is a 100% ambulatory role with a strong existing patient base, top-tier facilities, and a focus on quality, community-based cancer care.Position Highlights
  • Flexible Schedule opportunities (Full-time, part-time)
  • Balanced hematology and oncology mix
  • Average 12 patients per day
  • Modern infusion centers, on-site labs, imaging, and radiation oncology
  • Minimal call (1:7 rotation, phone only)
  • Open to new APP graduates or APPs with limited oncology experience
Compensation & Benefits
  • Annual salary: $120K–$140K with production bonus potential
  • 5 weeks PTO + 7 paid holidays
  • $2K CME stipend
  • Comprehensive health, dental, vision, and 401(k)
Why Hilton Head?Enjoy 12 miles of pristine beaches, world-class golf, and year-round outdoor living. Hilton Head offers the charm of a close-knit community with the amenities of a coastal resort—excellent schools, mild weather, and easy access to Savannah and Charleston.If you’re looking for a rewarding oncology role with autonomy, stability, and coastal lifestyle benefits, this is your chance to join a thriving practice in the Lowcountry of South Carolina.Jacob Bass, Senior Managing Consultant at AMN Healthcare, represents this position and would like to provide you with further details. To schedule a meeting with Jacob to discuss this opportunity, please click this link: https://calendly.com/jacob_bass. Engaging with Jacob directly will streamline your application process with minimal delays, ensuring you interact solely with individuals who represent this opportunity. 
View all Jobs in South Carolina

Statistics on Nurse Practitioner Jobs in South Carolina

At AMN Healthcare, we try to provide you with the data you need to make a decision about working a Nurse Practitioner permanent job in South Carolina. We’ve compiled information about salary ranges and trends over the last 3 months, along with other important statistics about types of healthcare facilities offering work in South Carolina so you have the latest at your fingertips.

Salary Range

Jobs by Facility types

Frequently Asked Questions about Permanent Nurse Practitioner Jobs in South Carolina

How many Nurse Practitioner jobs are currently available in South Carolina?

As of Dec 04, 2025, AMN Healthcare currently has 1 exclusive permanent Nurse Practitioner job opportunities waiting for you in South Carolina.

What is the salary range for permanent Nurse Practitioner jobs in South Carolina?

The pay rates for the available Nurse Practitioner Advanced Practice jobs in South Carolina range from $120k to $140k per year, providing competitive compensation options.

What is the average annual salary for Nurse Practitioner positions in South Carolina?

As of Dec 04, 2025, the average annual salary based on 2 permanent Nurse Practitioner jobs in South Carolina is $130k yearly, ensuring you are fairly rewarded for your expertise.

Can you tell me about historical salary trends in South Carolina for permanent Nurse Practitioner positions?

Based on historical data from the last year, the average annual salary for permanent Nurse Practitioner jobs in South Carolina, SC was $130k per year. The highest-paying position in South Carolina in the past year reached $140k annually, showcasing the potential for substantial earnings.

Are there flexible start dates available for these South Carolina Nurse Practitioner jobs?

Yes, as of Dec 04, 2025, AMN Healthcare offers permanent Nurse Practitioner Advanced Practice jobs in South Carolina with various starting dates to accommodate your schedule. Some options include a start date of Dec 18, 2025 (1 job).

What types of healthcare facilities offer permanent Nurse Practitioner jobs in South Carolina?

Our permanent Nurse Practitioner opportunities in South Carolina span across diverse healthcare settings, including Physician Group (2 jobs).

What Nurse Practitioner jobs are available at Physician Group facilities in South Carolina?

AMN Healthcare has 1 Nurse Practitioner jobs at Physician Group facilities in South Carolina with pay ranging from $120k to $140k per year as of Dec 04, 2025.

Healthcare Facilities in South Carolina that Offer Nurse Practitioner Jobs

These are just examples of some of the healthcare facilities in and around the South Carolina area that have historically offered permanent jobs for Nurse Practitioner professionals.

MUSC Health – Orangeburg
Departments
Hospitalist Nurse Practitioner, Neurology Physician, Nocturnist, Pediatric Hospital Medicine, and Pediatric Nurse Practitioner
Address
3000 Saint Matthews Rd
Orangeburg, SC 29118
Nearby Neighborhoods
Spring Valley (29115), Heatherwood (29115), Marshall Heights (29115), Glenwood Acres (29115), Colonial Heights (29115)
MUSC Health – Florence Medical Center
Departments
Cardiac Anesthesiology, Emergency Room Nurse Practitioner, Emergency Room Nurse Practitioner, Internal Medicine Nurse Practitioner, Nocturnist, and Radiology
Address
805 PAMPLICO HWY., #. 100550
Florence, SC 29505
Nearby Neighborhoods
Nob Hill (29501), Siesta Village (29501), Parkwood (29501), Fairlane Estates (29501), Crownland Estates (29501)
Grand Strand Medical Center
Departments
Laborist, Orthopedic, Pediatric Surgery, Surgical, Surgical, and Surgical Nurse Practitioner
Address
809 82ND PKWY., #. 7500
Myrtle Beach, SC 29572
Nearby Neighborhoods
Northwood (29572), Long Bay (29572), The Dunes (29572), Oakland Heights (29572), Cane Patch (29572)
MUSC Health Kershaw Medical Center
Departments
Diagnostic Radiology Physician, Pediatric Hospital Medicine, and Pediatric Nurse Practitioner
Address
1315 Roberts St
Camden, SC 29020
Nearby Neighborhoods
Edgewood (29021)
AFC Urgent Care Boiling Springs
Departments
Urgent Care Nurse Practitioner
Address
2746 Boiling Springs Road
Boiling Springs, SC 29316
* Estimate of payments is intended for informational purposes and includes hourly wages, as well as reimbursements for meal & incidental expenses and housing expenses incurred on behalf of the Company. Please speak with a recruiter for additional details.