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Locum Tenens Nurse Practitioner Advanced Practice Jobs in South Carolina

Explore Locums Nurse Practitioner Opportunities in South Carolina with AMN Healthcare

Are you a Nurse Practitioner Advanced Practice professional seeking locums job opportunities in South Carolina? Look no further! AMN Healthcare is your trusted partner in finding temporary positions that align with your career goals. With a total of 2 Locum Tenens Nurse Practitioner jobs currently available, your next exciting opportunity awaits.

Competitive Compensation for Temporary Nurse Practitioner Jobs in South Carolina Awaits You

When it comes to compensation, AMN Healthcare ensures that our locums opportunities are both rewarding and competitive. The pay rates for our current temporary Nurse Practitioner Advanced Practice jobs in South Carolina range from $198k per year to $214k yearly. In the last year, average pay rate based on 35 Nurse Practitioner jobs in was $201k per year. As of Oct 23, 2026, the average annual salary for available locum tenens Nurse Practitioner jobs stands at $206k per year.

Stay Informed About South Carolina Salary Trends for Locums Nurse Practitioner Jobs

Understanding the salary landscape is crucial when evaluating your career options. Based on historical data from the last year of posted locums tenens Nurse Practitioner jobs in South Carolina, the average annual salary remains steady at $201k per year. Additionally, the highest paying job in South Carolina for a temporary Nurse Practitioner position in the past year reached $280k annually, illustrating the potential for substantial earnings in the Nurse Practitioner field.

Flexible Start Dates in South Carolina to Suit Your Schedule

AMN Healthcare recognizes the importance of flexibility in your career. As of Oct 23, 2026, we offer temp Nurse Practitioner jobs in South Carolina with various starting dates, including Nov 5, 2026 (2 jobs). This flexibility allows you to plan your assignments according to your preferences, making your transition into a new role seamless.

Diverse South Carolina Facilities Hiring Nurse Practitioner

Temporary jobs in South Carolina for Nurse Practitioner Advanced Practices span across various healthcare facilities, including Short Term Acute Care Hospital (11 jobs) and Hospital (1 job) facilities. This diversity not only broadens your options for gaining new experience but also provides valuable networking opportunities.

Benefits of a Locums Nurse Practitioner Job in South Carolina

Opting for a temporary position offers unique benefits, including:

  • Variety and Adventure: Locums roles allow you to work in different settings and healthcare institutions around South Carolina, offering a diverse and enriching experience.
  • Flexibility: You have control over your schedule, enabling you to achieve a desirable work-life balance.
  • High Earning Potential: South Carolina locums positions often come with competitive pay rates, offering you the opportunity to earn a significant income while maintaining flexibility.
  • Skill Enhancement: Exposure to various healthcare environments enhances your clinical skills and adaptability.

Ready to embark on your next locums adventure? Explore our exclusive Locums Nurse Practitioner jobs in South Carolina on AMNHealthcare.com and take the first step towards a dynamic and rewarding career in healthcare. Your dream job is just a click away!

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Top Cities in South Carolina with Locum Tenens Nurse Practitioner Jobs

AMN Healthcare currently has 2 locum tenens Nurse Practitioner positions available in the state of South Carolina. Search the most recent jobs below, or click the button below to view all jobs.

Highest Paying Jobs in South Carolina

AMN Healthcare currently has locum tenens Nurse Practitioner positions available in South Carolina.
locum tenens
Pediatric Nurse Practitioner or Physician Assistant (NP/PA)
  • November 5, 2026
$102 to $110
Hourly Pay*
This facility is seeking a Pediatric Nurse Practitioner or Physician Assistant (NP/PA) for locum tenens support as they look to fill a current need. Details & requirements for this opportunity:
  • Schedule: 7 pm- 7 am
  • Job Setting: Hospital
  • Types of Cases: Must be comfortable with patients 32 weeks and resuscitation, Continuous positive airway pressure (CPAP), peripheral IVs, managing ventilators, administering pulmonary surfactant, umbilical lines, catheters, and other sick baby related procedures
  • Credentialing Timeframe: 30 Days
  • Must-Have an Active South Carolina License
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locum tenens
Oncology Nurse Practitioner or Physician Assistant (NP/PA)
  • November 5, 2026
$102 to $110
Hourly Pay*
This facility is seeking an Oncology Nurse Practitioner or Physician Assistant (NP/PA) for locum tenens support as they look to fill a current need.  Details and requirements for this opportunity: • Schedule: Monday-Friday, 8:30a-4:30p plus call • Practice Setting: Outpatient clinic and inpatient call • Type of cases and required procedures: Management of Bone Marrow Transplants, Blood Bank, Orders Tests, Orders Images, Prescribes • Credentialing timeframe: 60 Days • EMR: Epic • Certifications required: Must have Basic Life Support (BLS) • Licensure required: Willing to license
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Statistics on Nurse Practitioner Locums Jobs in South Carolina

At AMN Healthcare, we try to provide you with the data you need to make a decision about working a Nurse Practitioner locum tenens job in South Carolina. We’ve compiled information about salary ranges and trends over the last 3 months, along with other important statistics about types of healthcare facilities offering work in South Carolina so you have the latest at your fingertips.

Salary Range

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Salary Trends

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Jobs by Facility types

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Frequently Asked Questions about Locum Tenens Nurse Practitioner Jobs in South Carolina

How many locums Nurse Practitioner jobs are currently available in South Carolina?

As of Oct 23, 2026, AMN Healthcare currently has 2 exclusive travel Nurse Practitioner job opportunities waiting for you in South Carolina.

What is the salary range for locum tenens Nurse Practitioner jobs in South Carolina?

The pay rates for the available locums Nurse Practitioner Advanced Practice jobs in South Carolina range from $141k to $280k per year, providing competitive compensation options.

What is the average annual salary for Nurse Practitioner locums positions in South Carolina?

As of Oct 23, 2026, the average annual salary based on 37 locum tenens Nurse Practitioner jobs in South Carolina is $202k yearly, ensuring you are fairly rewarded for your expertise.

Can you tell me about historical salary trends in South Carolina for travel Nurse Practitioner positions?

Based on historical data from the last year, the average annual salary for locum tenens Nurse Practitioner jobs in South Carolina was $201k per year. The highest-paying locums position in South Carolina in the past year reached $280k annually, showcasing the potential for substantial earnings.

Are there flexible start dates available for these South Carolina Nurse Practitioner jobs?

Yes, as of Oct 23, 2026, AMN Healthcare offers locum tenens Nurse Practitioner Advanced Practice jobs in South Carolina with various starting dates to accommodate your schedule. Some options include a start date of Nov 5, 2026 (2 jobs).

What types of healthcare facilities offer locum tenens Nurse Practitioner jobs in South Carolina?

Our locum tenens Nurse Practitioner opportunities in South Carolina span across diverse healthcare settings, including Short Term Acute Care Hospital (11 jobs) and Hospital (1 job).

What locums Nurse Practitioner jobs are available at Short Term Acute Care Hospital facilities in South Carolina?

AMN Healthcare has 2 locums Nurse Practitioner jobs at Short Term Acute Care Hospital facilities in South Carolina with pay ranging from $198k to $214k per year as of Oct 23, 2026.

How can I find out when new locums jobs open in South Carolina?

New locums positions in South Carolina are added as healthcare facilities post them, so openings can change quickly. Download the AMN Passport app or create an AMN Healthcare profile to set job alerts, save searches, and get notified when roles that match your experience become available. An AMN recruiter can also let you know about upcoming opportunities.

Places in or Nearby South Carolina Where Locums Nurse Practitioner Jobs Are Located

In South Carolina, facilities like MUSC Health Kershaw Medical Center, MUSC Health – Orangeburg and MUSC Health – Florence Medical Center all have departments that hire for locum tenens Nurse Practitioner jobs. These facilities are nearby to cities like Camden (zip code 29020), Orangeburg (zip code 29118) and Florence (zip code 29505).

Other nearby states to South Carolina that offer Nurse Practitioner Advanced Practices jobs are North Carolina (118.2 miles, Zip Codes 27294, 28262, 27106), Georgia (168.1 miles, Zip Codes 30642, 31904, 31782) and West Virginia (312.2 miles, Zip Codes 25601, 25705, 25708). These are near to zip codes: 27294 (118.2 miles).

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Healthcare Facilities in South Carolina that Offer Locums Nurse Practitioner Jobs

These are just examples of some of the healthcare facilities in and around the South Carolina area that have historically offered travel jobs for Nurse Practitioner professionals.

AFC Urgent Care Boiling Springs
AFC Urgent Care Boiling Springs is a hospital located at 2746 Boiling Springs Road in Boiling Springs, SC, with an urgent care department. As a hospital-based urgent care setting staffed by physicians and advanced practice providers, it serves the role of providing unscheduled evaluation and treatment for acute, non-emergent conditions.
2746 Boiling Springs Road, Boiling Springs, SC 29316
Departments
Urgent Care
Hilton Head Hospital
Hilton Head Hospital is a short-term acute care hospital located at 25 Hospital Center Blvd, Hilton Head Island, SC. Its clinical departments include a broad mix of surgical and perioperative services (OR, CVOR, PACU, sterile processing), emergency care and critical care units (ER, ICU, PCU, NICU), maternal and pediatric services (Labor & Delivery, postpartum, pediatrics), and diagnostic services such as laboratory, computed tomography, nuclear medicine and echocardiography, with additional specialties including vascular and medical-surgical units. The facility employs physicians, advanced practice providers, nursing staff and allied health professionals.
25 Hospital Center Blvd, Hilton Head Island, SC 29926
Departments
ER, Laboratory, Echo, OR, Computed Tomography, Labor & Delivery, MS, Pedi, PCU, ICU, NICU, Postpartum, CVOR, Adult, Vascular, Acute, Nuclear Medicine, PACU, and Sterile Processor
Shifts: 8 D, 10 D, 10 E, 10 N, 12 D, 12 E, and 12 N
Durations: 6 wks, 8 wks, 12 wks, 13 wks, 14 wks, 26 wks, and 118 wks
MUSC Health – Florence Medical Center
MUSC Health – Florence Medical Center is a short-term acute care hospital at 805 Pamplico Hwy., #. 100550 in Florence, SC, near Nob Hill and Siesta Village. Departments include Internal Medicine, ER and Cardiac, and the facility’s clinical staff is composed of advanced practice providers and physicians.
805 PAMPLICO HWY., #. 100550, FLORENCE, SC 29505
Departments
Internal Medicine, ER, and Cardiac
MUSC Health – Orangeburg
MUSC Health – Orangeburg is a short-term acute care hospital located at 3000 Saint Matthews Rd in Orangeburg, SC, near the Spring Valley and Heatherwood neighborhoods. The facility lists Hospitalist and Mammography departments and notes physicians and advanced practice clinicians among its clinical professions. Short-term acute care hospitals with hospitalist services and mammography typically provide inpatient medical management and diagnostic breast imaging supported by physician and advanced practice teams.
3000 Saint Matthews Rd, Orangeburg, SC 29118
Departments
Hospitalist and Mammography
MUSC Health Columbia Medical Center Northeast
MUSC Health Columbia Medical Center Northeast is a short-term acute care hospital located at 120 Gateway Corporate Blvd in Columbia, SC, near Brickyard Village and Fairfield Arms. Clinical departments include Pedi, and the medical staff comprises physicians and advanced practice providers. As a short-term acute care hospital staffed by physicians and advanced practice clinicians, it provides hospital-based diagnostic, medical, and procedural care typical for this facility type.
120 Gateway Corporate Blvd, Columbia, SC 29203
Departments
Pedi
MUSC Health Kershaw Medical Center
MUSC Health Kershaw Medical Center is a short-term acute care hospital located at 1315 Roberts St in Camden, SC, near the Edgewood neighborhood. Clinical departments include Pedi and Hospitalist services, and the facility staffs physicians and advanced practice clinicians. As a short-term acute care hospital, it provides acute inpatient and stabilization services delivered through physician-led and advanced practice provider teams.
1315 Roberts St, Camden, SC 29020
Departments
Pedi and Hospitalist
St Francis Downtown
St Francis Downtown is a short-term acute care hospital at 1 Saint Francis Dr in Greenville, SC, near Mountain View Homes and University Ridge Homes. Departments include Diagnostic Radiology with mammography and teleradiology capability, a cardiovascular operating room (CVOR), and Oncology. The medical staff includes physicians and advanced practice clinicians.
1 Saint Francis Dr, Greenville, SC 29601
Departments
Diagnostic Radiology, Teleradiology, CVOR, Mammography, and Oncology
Trident Medical Center
TJC
For-Profit
Trident Medical Center is a short-term acute care hospital located at 9330 Medical Plaza Dr in Charleston, SC, near the Huntington Woods and Parkshire neighborhoods; it was established in 1975, is for-profit, has 497 beds and is accredited by TJC. Clinical capacity includes 22 operating rooms, two cardiac catheterization labs, six endoscopy rooms and a wide range of diagnostic and therapeutic services such as CT, MRI, PET, nuclear medicine, extracorporeal shockwave lithotripsy, dialysis and comprehensive perioperative and rehabilitation services. Departments span emergency and designated trauma services, multiple critical care units (CVICU, CCU, medical/surgical ICU, pediatric ICU), obstetrics and neonatal nursery, cardiothoracic and vascular surgery, interventional and diagnostic radiology, inpatient and outpatient psychiatry, burn care and CARF inpatient rehabilitation, among others. The medical staff includes physicians, advanced practice providers, nursing, allied health and support services, the facility hosts allopathic, osteopathic, dental, podiatric and other residency programs, and operates with a workforce equivalent to approximately 2,217 full-time positions.
9330 Medical Plaza Dr, CHARLESTON, SC 29406
497 certified beds 22 operating rooms Established 1975
SERVICES
Pharmacy
Acute Renal Dialysis
Anesthesia
Audiology
Chemotherapy
Departments
Magnetic Resonance Imaging, Surgical, Dialysis, Hospitalist, OB/GYN, Interventional Radiology, Radiology, Vascular, Acute, CVOR, PACU, OR, Psych, ICU, Computed Tomography, PCU, Echo, EEG, Rehab, Cath Lab, Case Manager, EP Lab, Positron Emission Tomography, Telemetry, CVICU, MS, Diagnostic, Nuclear Medicine, Trauma, Critical Care, Adult Inpatient Psychiatric, Burn Care Unit, Cardiac Catheterization Lab, Open Heart / Cardiothoracic Surgery, CARF Inpatient Rehabilitation, Coronary Care Unit (CCU), Designated Trauma Center, Emergency Department, Emergency Psychiatric, Gerontological Specialty, Inpatient Surgical, Intensive Care Unit (Medical/Surgical ICU), Neonatal Nursery, Neurosurgical, Obstetrics (OB/L&D), Orthopedic Surgery (Hospital), Outpatient Psychiatric, Outpatient Rehabilitation, Outpatient Surgery, Pediatric, Pediatric ICU, Reconstructive Surgery, Surgical ICU, Psychiatric Unit, and Rehabilitation Unit
Shifts: 8 D, 8 E, 8 N, 9 D, 10 D, 10 E, 10 N, 12 D, 12 E, and 12 N
Durations: 6 wks, 8 wks, 11 wks, 12 wks, 13 wks, 15 wks, and 26 wks

Find Other Types of Nurse Practitioner Jobs in South Carolina

* Estimate of payments is intended for informational purposes and includes hourly wages, as well as reimbursements for meal & incidental expenses and housing expenses incurred on behalf of the Company. Please speak with a recruiter for additional details.