Nursing License and Renewal Mississippi

Navigate the Licensure Journey with AMN Healthcare

Mississippi is a unique blend of old and new, historic and contemporary, metropolitan and rural. The Magnolia State is the birthplace of the delta blues, riverboat gaming and the Stetson hat. Mississippi is also the hometown of some of today's most well known celebrities including Elvis, Oprah and B.B. King.

AMN Healthcare is here to guide you through the Mississippi nursing licensure process and can even help you find your next Mississippi travel nursing job.

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Step-by-Step Guide to Securing Your Nursing License in Mississippi

The requirements for Mississippi RN licensure by endorsement:

  • Register with the state board’s Nurse Gateway portal and submit a completed application for endorsement
  • Pay the RN license application fee of $100 ($60 for LPN licenses)
  • After completing the endorsement application, register for a criminal background check, pay the $75 fee and complete fingerprinting
  • Request an official transcript from your nursing program, which must be sent to the Mississippi State Board of Nursing in a sealed envelope or via eScrip-Safe.
  • Submit verification of your original license by visiting; if you were originally licensed in a state that does not participate in NURSYS verification, you will need to contact your original board of nursing to request verification.

How to Renew Your License

The state’s nurse license period is for two years, based upon the renewal cycle of the license. Registered nurses can renew their RN license in Mississippi by submitting a renewal application via the Nurse Gateway portal and paying the RN license fee during the renewal period, from September 1 – December 31, in even-numbered years. LPNs can renew their licenses during odd-numbered years; LPNs with expanded role certificates have additional CE requirements.

Mississippi is a Compact Nursing State

Mississippi participates in the Nurse Licensure Compact (NLC), which allows RNs or LPNs to have one multistate nursing license, with the privilege to practice in any of the 30-plus compact member states. The licensing standards in NLC states require all applicants for a compact multistate nursing license to meet the same requirements.

If your original state of licensure is a compact state, you can verify whether you hold a multistate license or a single state license at If you do hold a multistate nursing license, you may work travel nursing jobs in Mississippi without the need for additional licensing.


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