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Registered Nurse Per Diem Jobs in Sioux Falls, SD

Information About Per Diem RN Positions in Sioux Falls

At AMN Healthcare, we understand the dynamic needs of nursing professionals seeking per diem Registered Nurse opportunities in Sioux Falls, and we are here to guide you every step of the way. With over 40 years of experience as a staffing leader, we proudly support more than 10,000 healthcare workers annually, offering personalized guidance tailored to your unique career aspirations. Whether you are interested in roles such as Medical Surgical, Telemetry, Emergency Room, Intensive Care Unit, or specialized fields including Labor & Delivery, Pediatric Intensive Care Unit, or Home Health, AMN Healthcare connects you with rewarding positions that fit your lifestyle and expertise. Explore a diverse range of opportunities across multiple settings, and let us help you navigate your nursing career with the support and resources you deserve. Your future in healthcare starts here!

Research High-Paying Registered Nurse Opportunities in Sioux Falls, SD

A few of the highest paying Registered Nurse jobs available in Sioux Falls, SD include:

AMN Healthcare is currently offering 8 per diem Registered Nurse job opportunities in Sioux Falls, SD, with hourly pay ranging from $35 to $45 and an average of $40 per hour. These positions span a variety of specialties including Medical Surgical Registered Nurse, Progressive Care Unit Registered Nurse, and Telemetry RN. With start dates available as early as 12/18/25 (8 jobs), professionals can quickly secure a role that aligns with their career goals.

Jobs are available in zip codes 57105, with additional opportunities in nearby cities such as Tyler (57.7 miles), Yankton (58.6 miles), and Mitchell (67.4 miles). Whether you’re looking to explore new locations or gain diverse clinical experience, we’re here to help you find the perfect per diem Registered Nurse job. Just click Apply Now and we’ll match you with a recruiter to help you find your next Registered Nurse position in or near Sioux Falls!

Registered Nurse Facilities and Duties in Sioux Falls

Sioux Falls, South Dakota, offers a diverse array of opportunities for Registered Nurses across multiple specialties, making it an ideal location for healthcare professionals seeking vibrant and fulfilling careers. Nurses can work in various settings, including bustling medical-surgical units, specialized intensive care units, and emergency departments, providing critical care in high-pressure environments. For those interested in procedural nursing, the operating room, cath lab, and endoscopy suites present dynamic roles that involve patient preparation and surgical assistance. Additionally, the growing need for community-focused roles in home health, hospice, and outpatient clinics allows nurses to deliver compassionate care directly to patients in their homes and local facilities. Opportunities abound in pediatrics, where nurses can work in neonatal intensive care units or pediatric emergency rooms, as well as in rehabilitation settings, case management, and outpatient services. With its supportive healthcare community, Sioux Falls invites dedicated nursing professionals to contribute to quality care in an engaging and rewarding environment.

Reasons RN Professionals Like to Work a Per Diem Job in Sioux Falls, South Dakota

As a Registered Nurse professional considering per diem opportunities in Sioux Falls, South Dakota, you’ll find a vibrant community that perfectly blends work-life balance with a great quality of living. Sioux Falls boasts a reasonable cost of living, allowing you to enjoy charming neighborhoods like the historic Cathedral District and the up-and-coming downtown area filled with local shops, cafes, and breweries. The area’s four distinct seasons bring plenty of sunshine, with warm summers perfect for outdoor adventures and snowy winters ideal for cozying up by the fire after a long shift. In your downtime, take advantage of the stunning Falls Park, explore the SculptureWalk downtown, or immerse yourself in the local arts scene at the Washington Pavilion. With a welcoming atmosphere, beautiful surroundings, and ample recreational activities, Sioux Falls offers the perfect backdrop for your nursing career.

Find Your Ideal Per Diem Registered Nurse Jobs in Sioux Falls

Explore our diverse selection of per diem Registered Nurse job opportunities in Sioux Falls, where you can find the perfect role that fits your skills and lifestyle. Take a moment to browse through the listings below and discover the ideal position that aligns with your passion for patient care!

per diem Exclusive
Post Anesthesia Care Unit Nurse (PACU RN)
  • Sioux Falls, South Dakota – 57105
  • 12 D,
  • December 18, 2025
$42 to $45
Hourly Pay*
PACU RN's monitor post-operation vital signs, levels of consciousness, and assure patients safely wake from anesthesia after surgery. PACU RN’s treat pain, nausea, and other patient post-op symptoms, and any side effects of anesthesia. PACU RN’s work in the post-Anesthesia care unit at a hospital; can also be known as the recovery room. Education/Requirements:
  • Bachelor of Science in Nursing (BSN): 4-Year Education 
  • Associates Degree in Nursing (ADN): 2-Year Education 
  • You must earn an ADN or BSN degree and pass the NCLEX to apply for a license as a RN. 
  • RN‘s can only work with an active state license.
  • ACLS, CPAN and PALS are often required
per diem Exclusive
Post Anesthesia Care Unit Nurse (PACU RN)
  • Sioux Falls, South Dakota – 57105
  • 12 N,
  • December 18, 2025
$42 to $45
Hourly Pay*
PACU RN's monitor post-operation vital signs, levels of consciousness, and assure patients safely wake from anesthesia after surgery. PACU RN’s treat pain, nausea, and other patient post-op symptoms, and any side effects of anesthesia. PACU RN’s work in the post-Anesthesia care unit at a hospital; can also be known as the recovery room. Education/Requirements:
  • Bachelor of Science in Nursing (BSN): 4-Year Education 
  • Associates Degree in Nursing (ADN): 2-Year Education 
  • You must earn an ADN or BSN degree and pass the NCLEX to apply for a license as a RN. 
  • RN‘s can only work with an active state license.
  • ACLS, CPAN and PALS are often required
per diem Exclusive
Telemetry Nurse (TELE RN)
  • Sioux Falls, South Dakota – 57105
  • 12 D,
  • December 18, 2025
$38 to $41
Hourly Pay*
Telemetry RN's monitor patients’ vital signs by reading and analyzing an electrocardiogram, or another life sign-measuring device. Tele RN's are required for post-ICU care. Tele RN’s monitor critically ill patients: most are cardiac cases.  Tele RN's typically work in a hospital setting. Tele RN’s care for patients who are out of the ICU, but need their vital signs monitored closely (after surgery, for example). Education/Requirements:
  • Bachelor of Science in Nursing (BSN): 4-Year Education 
  • Associates Degree in Nursing (ADN): 2-Year Education 
  • You must earn an ADN or BSN degree and pass the NCLEX to apply for a license as a RN. 
  • RN‘s can only work with an active state license.
  • ACLS and TELE are often required
per diem Exclusive
Telemetry Nurse (TELE RN)
  • Sioux Falls, South Dakota – 57105
  • 12 N,
  • December 18, 2025
$38 to $41
Hourly Pay*
Telemetry RN's monitor patients’ vital signs by reading and analyzing an electrocardiogram, or another life sign-measuring device. Tele RN's are required for post-ICU care. Tele RN’s monitor critically ill patients: most are cardiac cases.  Tele RN's typically work in a hospital setting. Tele RN’s care for patients who are out of the ICU, but need their vital signs monitored closely (after surgery, for example). Education/Requirements:
  • Bachelor of Science in Nursing (BSN): 4-Year Education 
  • Associates Degree in Nursing (ADN): 2-Year Education 
  • You must earn an ADN or BSN degree and pass the NCLEX to apply for a license as a RN. 
  • RN‘s can only work with an active state license.
  • ACLS and TELE are often required
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Job Market Statistics for Per Diem Registered Nurse Professionals in Sioux Falls

As you explore the data presented below, you’ll gain valuable insights into the landscape of per diem Registered Nurse positions available in Sioux Falls. Our comprehensive statistics detail pay trends over the last three months, highlighting average earnings while also showcasing the minimum and maximum compensation for roles in the past year. This information is essential for anyone looking to navigate the current job market and understand the financial opportunities waiting for qualified nursing professionals in the area.

In addition to pay information, the charts provide a breakdown of healthcare facilities currently hiring in Sioux Falls, allowing you to see the diverse range of employers seeking skilled nurses. By leveraging this data, you can make informed decisions about your career path, aligning your skills and experience with the opportunities that fit your financial and professional aspirations. Whether you’re a seasoned nurse or just starting your journey, this information is a valuable resource to help you thrive in Sioux Falls’ dynamic healthcare landscape.

Salary Range

Jobs by Facility types

Frequently Asked Questions about Per Diem RN Jobs near Sioux Falls, SD

What is the average pay for a Per Diem RN job in Sioux Falls, South Dakota?

The average hourly pay for a Per Diem Registered Nurse job in Sioux Falls, South Dakota is approximately $40 per hour for Medical Surgical RN, Telemetry Registered Nurse, and Emergency Room RN. This data was last updated on December 4, 2025.

What is the highest hourly pay for a Per Diem Registered Nurse job in Sioux Falls?

The highest hourly pay for a Registered Nurse Per Diem job in Sioux Falls is $45 per hour for a ER RN. This data was last updated on December 4, 2025.

What types of experience are most commonly required for a Per Diem Registered Nurse job in Sioux Falls?

Most per diem Registered Nurse positions in Sioux Falls typically require a valid nursing license and relevant clinical experience in acute care settings. Additionally, familiarity with electronic medical records and strong communication skills are often essential.

What types of job opportunities are typically available for RN Per Diem positions in Sioux Falls?

Registered Nurse professionals seeking Per Diem positions in Sioux Falls can find opportunities in a variety of job types, including travel and per diem roles, including travel and per diem roles. These positions are available in specialized fields such as Medical Surgical, Progressive Care Unit, and Telemetry, offering flexibility and career growth in diverse healthcare settings.

What types of healthcare facilities in Sioux Falls typically offer Per Diem positions for Registered Nurse professionals?

In Sioux Falls, per diem positions for Registered Nurse professionals are typically found in hospitals, outpatient clinics, and rehabilitation centers. These facilities often require flexible staffing solutions to accommodate varying patient needs and busy periods.

What types of specialties are common for a Registered Nurse professional working a Per Diem job in Sioux Falls, South Dakota?

In Sioux Falls, South Dakota, common specialties for Registered Nurses working per diem jobs typically include emergency medicine, critical care, and surgical nursing. There is also a demand for nurses in areas such as orthopedics and geriatrics due to the diverse healthcare needs of the population. Furthermore, positions in outpatient clinics and home health nursing are prevalent, reflecting the growing emphasis on community care. These specialties allow for flexibility while meeting the varying healthcare demands of the region.

What are some keys reasons a Per Diem Registered Nurse professional might consider seeking a Medical Surgical, Telemetry, and Emergency Room job in Sioux Falls?

Per diem Registered Nurses might find Sioux Falls appealing due to its competitive pay rates and a growing demand for healthcare professionals, ensuring ample job opportunities. Additionally, the city’s quality of life, friendly community, and access to various outdoor activities can enhance both personal and professional fulfillment.

What are some most popular areas in Sioux Falls a Per Diem RN professionals would prefer to work and live?

Per diem Registered Nurse professionals in Sioux Falls often prefer areas like downtown for its vibrant atmosphere and accessibility to various healthcare facilities. They may also favor neighborhoods such as Prairie Green for its family-friendly environment and proximity to amenities. Additionally, the Elmwood area is appealing due to its blend of residential comfort and access to nature, making it a great choice for work-life balance.

What important factors should a Per Diem Registered Nurse professionals consider when evaluating a new position?

When evaluating a new per diem position, Registered Nurses should consider the overall compensation package, including hourly pay, benefits, and potential for overtime. Additionally, the work environment and flexibility in scheduling can significantly impact job satisfaction and work-life balance. Finally, assessing the reputation of the facility and the support provided to per diem staff is crucial for ensuring a positive work experience.

Which US Cities Offer Job Opportunities Similar to Sioux Falls for Registered Nurse Professionals

One city that shares similarities with Sioux Falls is Fargo, North Dakota. Like Sioux Falls, Fargo has a growing healthcare sector, driven in part by the presence of substantial medical facilities such as Essentia Health and Sanford Health. The cost of living in Fargo is comparable to Sioux Falls, with affordable housing options, both in single-family homes and apartments. The climate features cold winters and warm summers similar to Sioux Falls, allowing for outdoor activities year-round. Fargo also has a vibrant arts scene, featuring local theater productions and numerous festivals, providing nursing professionals with a balanced lifestyle.

Another city to consider is Rapid City, South Dakota. As the gateway to the Black Hills, Rapid City offers a unique combination of natural beauty and healthcare opportunities. The cost of living is reasonable, with various housing options that cater to different budgets. Rapid City’s healthcare facilities, including Regional Health hospitals, provide ample job opportunities for registered nurses, particularly in Medical Surgical and Telemetry. The city’s climate features mild summers and chilly winters; outdoor recreation, including hiking and biking, is a significant draw, promoting an active lifestyle alongside a supportive community atmosphere.

Lincoln, Nebraska, is also a noteworthy option for Registered Nurses. The city boasts a robust healthcare infrastructure with several hospitals and clinics, such as the Bryan Health system, which fosters an excellent work environment for nursing professionals in various specialized fields, including Emergency Room services. The overall cost of living in Lincoln is quite affordable, making it easy for nurses to find comfortable housing. With a climate that experiences all four seasons and a diverse range of cultural events, such as local sports and art festivals, Lincoln provides a rich lifestyle for those who enjoy community engagement and outdoor activities.

Springfield, Missouri, presents another excellent alternative. Known for its extensive healthcare network, including CoxHealth and Mercy Health, Springfield offers numerous job opportunities for registered nurses in Medical Surgical and Emergency Room settings. The cost of living in Springfield is lower than the national average, with a mix of housing options from urban apartments to suburban homes. The climate features warm summers and mild winters, which encourages residents to engage in outdoor activities in the nearby Ozarks. Springfield has a vibrant cultural scene with a variety of entertainment options and events, allowing for a well-rounded lifestyle.

Finally, Bismarck, North Dakota, could be an appealing city for those in the nursing profession. Bismarck offers a strong community-centric feel accompanied by healthcare institutions like Sanford Health and the Bismarck Cancer Center, creating a variety of career prospects for nurses. The cost of living remains economical, with reasonable housing costs that support families and individuals alike. The weather is characterized by cold winters and warm summers, promoting various seasonal activities. The city also has a wealth of historical attractions and outdoor recreational opportunities, fostering a lifestyle that values both professional growth and personal enjoyment.

Sioux Falls Healthcare Facilities With a History of Hiring Per Diem Registered Nurse Professionals

Sioux Falls boasts a variety of reputable healthcare facilities that frequently seek skilled Registered Nurses for per diem opportunities in Medical-Surgical, Telemetry, and Emergency Room settings. These positions offer flexibility and the chance to work in dynamic environments, making Sioux Falls an attractive destination for nursing professionals looking to advance their careers while meeting critical patient care needs.

Avera McKennan Hospital and University Health Center
Shifts
12 D and 12 N
Address
1325 S Cliff Ave
Sioux Falls, SD 57105
* Estimate of payments is intended for informational purposes and includes hourly wages, as well as reimbursements for meal & incidental expenses and housing expenses incurred on behalf of the Company. Please speak with a recruiter for additional details.